MLchartDataset catalogue

Sapitinib

Term · Oncology and biomedicine · MLC-T-ONC-016640

An erbB receptor tyrosine kinase inhibitor with potential antineoplastic activity. Sapitinib binds to and inhibits erbB tyrosine receptor kinases, which may result in the inhibition of cellular proliferation and angiogenesis in tumors expressing erbB. The erbB protein family, also called the epidermal growth factor receptor (EGFR) family, plays major roles in tumor cell proliferation and tumor vascularization.

Table 1. Record
IdentifierMLC-T-ONC-016640
FieldOncology and biomedicine
SynonymsErbB kinase inhibitor AZD8931
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON
{
  "id": "MLC-T-ONC-016640",
  "term": "Sapitinib",
  "field": "Oncology and biomedicine",
  "definition": "An erbB receptor tyrosine kinase inhibitor with potential antineoplastic activity. Sapitinib binds to and inhibits erbB tyrosine receptor kinases, which may result in the inhibition of cellular proliferation and angiogenesis in tumors expressing erbB. The erbB protein family, also called the epidermal growth factor receptor (EGFR) family, plays major roles in tumor cell proliferation and tumor vascularization.",
  "synonyms": [
    "ErbB kinase inhibitor AZD8931"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/sapitinib/"
}

Record 14,673 of 17,717 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.