selective cytokine inhibitory drug CC-1088

{
  "id": "MLC-T-ONC-016665",
  "term": "selective cytokine inhibitory drug CC-1088",
  "field": "Oncology and biomedicine",
  "definition": "An analog of thalidomide with potential antineoplastic activity that belongs to the functional class of agents called selective cytokine inhibitory drugs (SelCIDs). SelCIDs inhibit phosphodiesterase-4 (PDE 4), an enzyme involved in tumor necrosis factor alpha (TNF alpha) production. CC-1088 inhibits production of the cytokines vascular endothelial growth factor (VEGF) (a pro-angiogenic factor) and interleukin-6 (IL-6).",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/selective-cytokine-inhibitory-drug-cc-1088/"
}