sedoxantrone trihydrochloride
Term · Oncology and biomedicine · MLC-T-ONC-007631
A substance being studied in the treatment of some types of cancer. Sedoxantrone trihydrochloride binds to DNA and stops cells, including cancer cells, from repairing damage to DNA and from making more DNA, RNA, and protein. It is a type of DNA intercalator. Also called CI-958.
The trihydrochloride salt of the anthrapyrazole antineoplastic antibiotic sedoxantrone with potential antineoplastic activity. Sedoxantrone intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis.
| Identifier | MLC-T-ONC-007631 |
|---|---|
| Field | Oncology and biomedicine |
| Synonyms | CI-958 |
| References | NCI Dictionary of Cancer Terms; National Cancer Institute Thesaurus (CC BY 4.0) |
Record as JSON
{
"id": "MLC-T-ONC-007631",
"term": "sedoxantrone trihydrochloride",
"field": "Oncology and biomedicine",
"definitions": [
"A substance being studied in the treatment of some types of cancer. Sedoxantrone trihydrochloride binds to DNA and stops cells, including cancer cells, from repairing damage to DNA and from making more DNA, RNA, and protein. It is a type of DNA intercalator. Also called CI-958.",
"The trihydrochloride salt of the anthrapyrazole antineoplastic antibiotic sedoxantrone with potential antineoplastic activity. Sedoxantrone intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis."
],
"synonyms": [
"CI-958"
],
"references": [
"NCI Dictionary of Cancer Terms",
"National Cancer Institute Thesaurus"
],
"url": "https://mlchart.com/terminology/oncology/sedoxantrone-trihydrochloride/"
}
Record 14,783 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.