six TAAs-specific autologous T cells MT-601

{
  "id": "MLC-T-ONC-016769",
  "term": "six TAAs-specific autologous T cells MT-601",
  "field": "Oncology and biomedicine",
  "definition": "A preparation of autologous, ex vivo-expanded, CD4- and CD8-positive T lymphocytes specific for six tumor-associated antigens (TAAs), with potential immunomodulating and antineoplastic activities. Upon administration of six TAAs-specific autologous T cells MT-601, the T cells target, bind to and induce selective toxicity in cancer cells overexpressing one or more of these six TAAs. By targeting more than one antigen, MT-601 may be able to induce a better and more durable anti-tumor response due to its ability to overcome antigen loss.",
  "synonyms": [
    "multi-TAA-specific autologous T cells MT-601",
    "multi-tumor-associated antigen-specific autologous T cells MT-601",
    "multi-antigen specific CD4+ andCD8+ autologous T cells MT-601",
    "autologous T-cells-targeting six TAAs MT-601"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/six-taas-specific-autologous-t-cells-mt-601/"
}