mRNA-derived lung cancer vaccine BI 1361849

{
  "id": "MLC-T-ONC-015310",
  "term": "mRNA-derived lung cancer vaccine BI 1361849",
  "field": "Oncology and biomedicine",
  "definition": "A non-small cell lung cancer (NSCLC) vaccine containing six modified mRNAs, which encode six different NSCLC associated antigens, with potential antitumor and immunomodulatory activities. Upon intradermal administration, mRNA-derived lung cancer vaccine BI 1361849 may stimulate the immune system to mount both humoral and cellular responses against NSCLC cells. The six tumor-associated antigens (TAAs) encoded by these mRNAs are frequently expressed by NSCLC cells and are minimally expressed or absent in normal, healthy cells.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/mrna-derived-lung-cancer-vaccine-bi-1361849/"
}