p53 synthetic long peptide (70-251) vaccine

{
  "id": "MLC-T-ONC-015750",
  "term": "p53 synthetic long peptide (70-251) vaccine",
  "field": "Oncology and biomedicine",
  "definition": "A peptide vaccine consisting of 10 synthetic long peptides (SLPs), 25-30 amino acids in size and derived from the middle portion of p53 (amino acids 70-251), mixed with the adjuvant Montanide ISA-51 with potential immunostimulatory and antitumor activities. Upon administration, p53 synthetic long peptide (70-251) vaccine may stimulate the host immune system to mount a cytotoxic T-cell lymphocyte (CTL) response against p53-expressing tumor cells. p53, a tumor associated antigen (TAA), may be overexpressed in variety of cancer cell types.",
  "abbreviation": "p53-SLP vaccine",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/p53-synthetic-long-peptide-70-251-vaccine/"
}