pentetic acid calcium
Term · Oncology and biomedicine · MLC-T-ONC-006484
A drug that protects healthy tissues from the toxic effects of anticancer drugs.
The calcium salt of pentetic acid, a synthetic chelating agent related to the chelating agent ethylenediaminetetraacetic acid (EDTA). Pentetic acid chelates with the metallic radioisotopic moieties of unbound, extracellular radioimmunotherapeutic agents, resulting in higher specific tumor cell binding of radioimmunotherpeutic agents; this results in improved tumor cell radiocytotoxicity and the sparing of normal cells and tissues from the radiocytotoxic effects of these agents.
| Identifier | MLC-T-ONC-006484 |
|---|---|
| Field | Oncology and biomedicine |
| Abbreviation | Ca-DTPA |
| Synonyms | calcium DTPA; Calcium Trisodium DTPA; Calcium Trisodium Pentetate; Trisodium Calcium Diethylenetriaminepentaacetate |
| References | NCI Dictionary of Cancer Terms; National Cancer Institute Thesaurus (CC BY 4.0) |
Record as JSON
{
"id": "MLC-T-ONC-006484",
"term": "pentetic acid calcium",
"field": "Oncology and biomedicine",
"definitions": [
"A drug that protects healthy tissues from the toxic effects of anticancer drugs.",
"The calcium salt of pentetic acid, a synthetic chelating agent related to the chelating agent ethylenediaminetetraacetic acid (EDTA). Pentetic acid chelates with the metallic radioisotopic moieties of unbound, extracellular radioimmunotherapeutic agents, resulting in higher specific tumor cell binding of radioimmunotherpeutic agents; this results in improved tumor cell radiocytotoxicity and the sparing of normal cells and tissues from the radiocytotoxic effects of these agents."
],
"abbreviation": "Ca-DTPA",
"synonyms": [
"calcium DTPA",
"Calcium Trisodium DTPA",
"Calcium Trisodium Pentetate",
"Trisodium Calcium Diethylenetriaminepentaacetate"
],
"references": [
"NCI Dictionary of Cancer Terms",
"National Cancer Institute Thesaurus"
],
"url": "https://mlchart.com/terminology/oncology/pentetic-acid-calcium/"
}
Record 12,922 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.