p-cadherin antagonist PF-03732010

{
  "id": "MLC-T-ONC-015872",
  "term": "p-cadherin antagonist PF-03732010",
  "field": "Oncology and biomedicine",
  "definition": "An agent that inhibits p-cadherin (cdh3), with potential antineoplastic activity. PF-03732010 binds to and inhibits the activity of p-cadherin. Inhibition of the activity of p-cadherin may inhibit tumor cell invasion and proliferation in p-cadherin expressing tumor cells. P-cadherin, a cell-surface protein and member of the cadherin family, is overexpressed in a variety of solid tumors, and plays a role in cell adhesion, motility, invasion and proliferation.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/p-cadherin-antagonist-pf-03732010/"
}