P-cadherin-targeting agent PF-06671008

{
  "id": "MLC-T-ONC-015874",
  "term": "P-cadherin-targeting agent PF-06671008",
  "field": "Oncology and biomedicine",
  "definition": "An agent that targets p-cadherin (CDH3), with potential antineoplastic activity. Upon administration, PF-06671008 binds to and inhibits the activity of p-cadherin; this may inhibit both invasion and proliferation of p-cadherin-expressing tumor cells. P-cadherin, a cell-surface protein and member of the cadherin family, is overexpressed in a variety of tumors and plays a role in cell adhesion, motility, invasion, and proliferation.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/p-cadherin-targeting-agent-pf-06671008/"
}