MLchartDataset catalogue

P-cadherin inhibitor PCA062

Term · Oncology and biomedicine · MLC-T-ONC-015873

An agent that inhibits p-cadherin, with potential antineoplastic activity. Upon intravenous infusion, PCA062 binds to and inhibits the activity of p-cadherin. Inhibition of the activity of p-cadherin may inhibit both invasion and proliferation of p-cadherin expressing tumor cells. P-cadherin, a cell-surface protein and member of the cadherin family, is overexpressed in a variety of tumors and plays a role in cell adhesion, motility, invasion, and proliferation.

Table 1. Record
IdentifierMLC-T-ONC-015873
FieldOncology and biomedicine
SynonymsP-CAD inhibitor PCA062
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON
{
  "id": "MLC-T-ONC-015873",
  "term": "P-cadherin inhibitor PCA062",
  "field": "Oncology and biomedicine",
  "definition": "An agent that inhibits p-cadherin, with potential antineoplastic activity. Upon intravenous infusion, PCA062 binds to and inhibits the activity of p-cadherin. Inhibition of the activity of p-cadherin may inhibit both invasion and proliferation of p-cadherin expressing tumor cells. P-cadherin, a cell-surface protein and member of the cadherin family, is overexpressed in a variety of tumors and plays a role in cell adhesion, motility, invasion, and proliferation.",
  "synonyms": [
    "P-CAD inhibitor PCA062"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/p-cadherin-inhibitor-pca062/"
}

Record 12,764 of 17,717 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.