P-cadherin inhibitor PCA062
Term · Oncology and biomedicine · MLC-T-ONC-015873
An agent that inhibits p-cadherin, with potential antineoplastic activity. Upon intravenous infusion, PCA062 binds to and inhibits the activity of p-cadherin. Inhibition of the activity of p-cadherin may inhibit both invasion and proliferation of p-cadherin expressing tumor cells. P-cadherin, a cell-surface protein and member of the cadherin family, is overexpressed in a variety of tumors and plays a role in cell adhesion, motility, invasion, and proliferation.
| Identifier | MLC-T-ONC-015873 |
|---|---|
| Field | Oncology and biomedicine |
| Synonyms | P-CAD inhibitor PCA062 |
| References | National Cancer Institute Thesaurus (CC BY 4.0) |
Record as JSON
{
"id": "MLC-T-ONC-015873",
"term": "P-cadherin inhibitor PCA062",
"field": "Oncology and biomedicine",
"definition": "An agent that inhibits p-cadherin, with potential antineoplastic activity. Upon intravenous infusion, PCA062 binds to and inhibits the activity of p-cadherin. Inhibition of the activity of p-cadherin may inhibit both invasion and proliferation of p-cadherin expressing tumor cells. P-cadherin, a cell-surface protein and member of the cadherin family, is overexpressed in a variety of tumors and plays a role in cell adhesion, motility, invasion, and proliferation.",
"synonyms": [
"P-CAD inhibitor PCA062"
],
"references": [
"National Cancer Institute Thesaurus"
],
"url": "https://mlchart.com/terminology/oncology/p-cadherin-inhibitor-pca062/"
}
Record 12,764 of 17,717 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.