Oncology and biomedicine terminology · MLC-0111

Oncology and biomedicine terms: P (1,454)

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• PericardiumThe thin, fluid-filled sac that surrounds the heart, including the top of the heart that is connected to...
• Pericytic tumorA type of soft tissue tumor that begins in cells that wrap around blood vessels. Pericytic tumors may be...
• PerifosineA substance that is being studied in the treatment of cancer. It belongs to the family of drugs called...
• Perihilar bile duct cancerCancer that forms in the area where the left and right hepatic ducts join just outside the liver and form the...
• Perihilar cholangiocarcinomaCancer that forms in the area where the left and right hepatic ducts join just outside the liver and form the...
• Perillyl alcoholA substance that is being studied in the prevention of cancer. It belongs to the family of plant drugs called...
• PerimenopausalDescribes the time in a woman’s life when menstrual periods become irregular as she approaches menopause...
• Perindopril erbumineThe tert-butylamine salt of perindopril, the ethyl ester of a non-sulfhydryl angiotensin converting enzyme...
• Perineal colostomyAn opening made surgically to allow the colon to exit the body through the perineum (the area of the body...
• PerineumThe area of the body between the anus and the vulva in females, and between the anus and the scrotum in males.
• PerineuralAround a nerve or group of nerves.
• Periodic neutropeniaA chronic condition that affects neutrophils (a type of white blood cell). In periodic neutropenia, the...
• PerioperativeAround the time of surgery. This usually lasts from the time the patient goes into the hospital or doctor's...
• Peripheral bloodBlood circulating throughout the body.
• Peripheral blood lymphocyte therapyA treatment for Epstein-Barr virus infection or overgrowth of white blood cells (lymphocytes) after an organ...
• Peripheral blood smearA procedure in which a sample of blood is viewed under a microscope to count different circulating blood...
• Peripheral blood stem cell transplantA procedure in which a patient receives healthy blood-forming cells (stem cells) to replace their own stem...
• Peripheral neuropathyA nerve problem that causes pain, numbness, tingling, swelling, or muscle weakness in different parts of the...
• Peripheral primitive neuroectodermal tumorA type of cancer that forms in bone or soft tissue. Also called Ewing sarcoma and pPNET.
• Peripheral stem cellAn immature cell found circulating in the bloodstream. New blood cells develop from peripheral stem cells.
• Peripheral stem cell supportA procedure in which a patient receives healthy blood-forming cells (stem cells) to replace their own stem...
• Peripheral T-cell lymphomaOne of a group of aggressive (fast-growing) non-Hodgkin lymphomas that begin in mature T lymphocytes (T cells...
• Peripheral venous catheterA device used to draw blood and give treatments, including intravenous fluids, drugs, or blood transfusions...
• Peripherally inserted central catheterA device used to draw blood and give treatments, including intravenous fluids, drugs, or blood transfusions...
• PeristalsisThe rippling motion of muscles in the intestine or other tubular organs characterized by the alternate...
• PeritonealHaving to do with the parietal peritoneum (the tissue that lines the abdominal wall and pelvic cavity) and...
• Peritoneal carcinomatosisA serious condition in which cancer, usually of the digestive tract or female reproductive organs, spreads...
• Peritoneal cavityThe space within the abdomen that contains the intestines, the stomach, and the liver. It is bound by thin...
• Peritoneal fluidA liquid that is made in the abdominal cavity to lubricate the surface of the tissue that lines the abdominal...
• Peritoneal infusionA method of delivering fluids and drugs directly into the abdominal cavity through a thin tube. Also called...
• Peritoneal perfusionA method of delivering fluids and drugs directly to tumors in the peritoneal cavity.
• Peritoneal washingA procedure in which a salt-water solution is used to wash the peritoneal cavity and then is removed to check...
• PeritoneumThe tissue that lines the abdominal wall and covers most of the organs in the abdomen.
• PeritonitisInflammation of the peritoneum (tissue that lines the abdominal wall and covers most of the organs in the...
• Perivascular epithelioid cell tumorA family of rare tumors that form in the soft tissues of the stomach, intestines, lungs, female reproductive...
• Perivascular tumorA type of soft tissue tumor that begins in cells that wrap around blood vessels. Perivascular tumors may be...
• PerjetaA drug used with other drugs to treat breast cancer that is HER2 positive. It is used in patients whose...
• PERK inhibitor HC-5404-FUThe hemifumarate salt form of HC-5404, an orally bioavailable inhibitor of the serine/threonine kinase...
• PERK inhibitor NMS-03597812An orally bioavailable inhibitor of the serine/threonine kinase protein kinase R (PKR)-like endoplasmic...
• Pernicious anemiaA condition in which the body is unable to properly absorb vitamin B12, leading to a lower-than-normal number...
• Peroxisome proliferator-activated receptor gamma pathwayDescribes a group of proteins in a cell that work together to help control how certain genes are expressed...
• Personal health recordA collection of information about a person’s health that allows the person to manage and track his or her own...
• Personal historyA collection of information about a person’s health that allows the person to manage and track his or her own...
• Personal medical historyA collection of information about a person’s health that allows the person to manage and track his or her own...
• Personalized ALL-specific multi-HLA-binding peptide vaccineAn individualized peptide-based cancer vaccine comprised of three to five human leukocyte antigen (HLA)...
• Personalized and adjusted neoantigen peptide vaccine PANDA-VACA peptide-based, personalized cancer therapeutic vaccine consisting of up to 8 patient-specific tumor...
• Personalized cancer neoantigen vaccine GAd-PEVA personalized neoantigen priming vaccine comprised of a great ape (gorilla) adenoviral (GAd) vector encoding...
• Personalized cancer neoantigen vaccine MVA-PEVA personalized neoantigen booster vaccine comprised of a modified Vaccinia Ankara (MVA) viral vector encoding...
• Personalized genomic vaccine 001A synthetic peptide-based, personalized cancer vaccine consisting of multiple patient-specific tumor...
• Personalized liposomal neoantigen-based peptide vaccine EVX-01A personalized liposomal peptide vaccine composed of specific cancer neoepitopes, which are highly...
• Personalized live-attenuated double-deleted Listeria monocytogenesA proprietary, personalized live, attenuated, double-deleted (pLADD) strain of the Gram-positive bacterium...
• Personalized neoantigen DNA vaccine GNOS-PV01A personalized cancer vaccine consisting of patient-specific neoantigen-coding DNA plasmids, which are...
• Personalized neoantigen DNA vaccine GNOS-PVO2A personalized cancer vaccine consisting of patient-specific neoantigen-coding DNA plasmids, which are...
• Personalized neoantigen follicular lymphoma vaccineA peptide-based, personalized follicular lymphoma therapeutic vaccine consisting of up to 20 neoantigens and...
• Personalized neoantigen ovarian cancer vaccineA peptide-based, personalized ovarian cancer therapeutic vaccine consisting of up to 20 neoantigens and...
• Personalized neoantigen peptide vaccine iNeo-Vac-P01A peptide-based, personalized cancer vaccine consisting of patient-specific mutated long peptides, which are...
• Personalized neoantigen plasmid DNA melanoma vaccine EVX-02A plasmid DNA melanoma vaccine composed of DNA plasmid encoding multiple, melanoma patient-specific...
• Personalized neoantigen upper gastrointestinal tract cancer vaccineA personalized upper gastrointestinal (GI) tract cancer vaccine consisting of multiple patient-specific...
• Personalized neoantigen vaccine NECVAX NEO1A personalized, oral Ty21a-based neoantigen vaccine consisting of eukaryotic expression plasmid encoding...
• Personalized neoantigen-specific T lymphocytes NEO-PTC-01A preparation of autologous, personalized tumor neoantigen-specific T lymphocytes, with potential...
• Personalized neoepitope yeast vaccine YE-NEO-001A cancer vaccine composed of a heat-killed yeast that has been genetically modified to express...
• Personalized peptide cancer vaccine mBTCvaxA peptide-based, personalized cancer therapeutic vaccine consisting of patient-specific mutated tumor...
• Personalized peptides-loaded autologous dendritic cell vaccineA cell-based personalized cancer vaccine composed of autologous dendritic cells (DCs) loaded with the...
• Personalized polyepitope plasmid DNA breast cancer vaccineA polyepitope DNA vaccine composed of a DNA plasmid encoding multiple, highly immunogenic tumor-associated...
• Personalized synthetic long peptide breast cancer vaccineA cancer vaccine consisting of one or more long, synthetic peptides derived from patient-specific breast...
• Personalized synthetic long peptide vaccineA personalized peptide vaccine consisting of synthetic long peptides (SLPs), ranging from 20-35 amino acids...
• PerturbationA disruption or disturbance.
• PertussisA serious bacterial infection of the lungs and breathing tubes that spreads easily. Pertussis begins like a...
• PertuzumabA drug used with other drugs to treat breast cancer that is HER2 positive. It is used in patients whose...
• Pertuzumab, trastuzumab, and hyaluronidaseA combination of three drugs used with other drugs to treat adults with HER2-positive breast cancer. It is...
• Pertuzumab, trastuzumab, and hyaluronidase-zzxfA ready-to-use fixed-dose combination of pertuzumab and trastuzumab, both recombinant humanized monoclonal...
• Pertuzumab zuvotolimodAn immunotherapeutic composed of a monoclonal antibody directed against the tumor-associated antigen (TAA)...
• PesticideAny substance that is used to kill insects and other pests.
• PET scanA procedure in which a small amount of radioactive glucose (sugar) is injected into a vein, and a scanner is...
• PetadeferitrinAn orally bioavailable iron-chelating agent and derivative of desferrithiocin, with iron chelating and...
• PET-CT scanA procedure that combines the pictures from a positron emission tomography (PET) scan and a computed...
• PetechiaePinpoint, unraised, round red spots under the skin caused by bleeding.
• Pet-facilitated therapyA type of therapy that uses dogs or other pets to improve the physical and mental health of patients with...
• Petiveria alliacea extractAn herbal extract derived from the plant Petiveria alliacea, with potential antineoplastic activity...
• PET-MRI scanA procedure that combines the pictures from a positron emission tomography (PET) scan and a magnetic...
• PetrolatumA thick, greasy, substance with no odor or taste made from petroleum (mixture of oily liquids found in the...
• Petrolatum-mineral oil-lanolin-ceresin ointmentA petrolatum-based ointment absorbed by dry and moist skin, petrolatum-mineral oil-lanolin-ceresin ointment...
• Petroleum jellyA thick, greasy, substance with no odor or taste made from petroleum (mixture of oily liquids found in the...
• Peutz-Jeghers syndromeA rare genetic disorder in which many polyps (abnormal growths of tissue) form in the lining of the...
• PevonedistatA substance being studied in the treatment of some types of cancer. Pevonedistat blocks an enzyme called...
• Pexastimogene devacirepvecAn oncolytic thymidine kinase (TK)-deleted vaccinia poxvirus expressing human GM-CSF (hGM-CSF) with...
• Pexidartinib hydrochlorideA drug used to treat adults with tenosynovial giant cell tumor (a rare, usually benign tumor that affects the...
• PexmetinibAn orally bioavailable small-molecule inhibitor of p38 and Tie2 kinases with potential antineoplastic...
• PF-00299804A drug used to treat non-small cell lung cancer that has spread, has not already been treated, and has...
• PF-3512676A substance that is being studied in the treatment of some types of cancer. It belongs to the family of drugs...
• PFICA rare, inherited disorder marked by a buildup in the liver of bile (fluid that helps digest fat). This can...
• PFSThe length of time during and after the treatment of a disease, such as cancer, that a patient lives with the...
• PFTA test used to measure how well the lungs work. It measures how much air the lungs can hold and how quickly...
• PGOne of several hormone-like substances made by the body. Different PGs control blood pressure, contraction of...
• PGE1A drug that is used to treat impotence (inability to have an erection) and is being studied in the treatment...
• PGLA/PEG copolymer-based paclitaxelA controlled-release, intratumoral paclitaxel formulation in which paclitaxel is incorporated into a...
• p-glycoproteinA protein that pumps substances out of cells. Cancer cells that have too much p-glycoprotein may not be...
• P-glycoprotein inhibitor HM30181AKAn inhibitor of the adenosine triphosphate (ATP)-binding cassette (ABC) transporter P-glycoprotein (P-gp)...
• pHA measure of how acidic or basic a substance or solution is. pH is measured on a scale of 0 to 14. On this...
• pH low insertion peptide-exatecan conjugate CBX-12A conjugate composed of a pH low insertion peptide (pHLIP) linked to the camptothecin analog exatecan, with...
• PH20 hyaluronidase-expressing adenovirus VCN-01An oncolytic, replication-competent adenovirus encoding the human glycosylphosphatidylinositol-anchored...
• PHA-739358A substance being studied in the treatment of chronic myelogenous leukemia. PHA-739358 may stop tumor growth...
• PHACE syndromeA rare disorder marked by a hemangioma (a benign blood vessel tumor) that spreads across an area of the body...
• PhagocyteA type of immune cell that can surround and kill microorganisms, ingest foreign material, and remove dead...
• PhagocytosisThe process by which a phagocyte (a type of white blood cell) surrounds and destroys foreign substances (such...
• Phaleria macrocarpa Extract DLBS-1425An extract of the flesh from the fruit of Phaleria macrocarpa, an Indonesian herbal medicine, with potential...
• Phantom limb painThe sensation of pain or other unpleasant feelings in the place of a missing (phantom) limb.
• PharmacistA health professional who has special training in preparing and dispensing (giving out) prescription drugs...
• PharmacogeneticsThe study of how a person’s genes affect the way he or she responds to drugs. Pharmacogenetics is being used...
• PharmacogenomicsThe study of how a person’s genes affect the way he or she responds to drugs. Pharmacogenomics is being used...
• PharmacokineticsThe activity of drugs in the body over a period of time, including the processes by which drugs are absorbed...
• Pharmacologic substanceThe main ingredient in a medicine that causes the desired effect of the medicine. Some medicines contain more...
• Pharmacological ascorbateA high dose (HD) of ascorbic acid, a pro-oxidant agent, with potential antineoplastic and...
• PharmacologyThe study of the origin, chemistry, and uses of drugs and their effects on the body.
• PharmacopoeiaA book describing chemicals, drugs, and other substances and how they are used as medicines. It is prepared...
• PharmacovigilanceThe science and practice of continuously reviewing the safety of drugs as they are tested in clinical trials...
• Pharyngeal cancerCancer that forms in tissues of the pharynx. The pharynx is the hollow, muscular tube inside the neck that...
• PharyngectomySurgery to remove all or part of the pharynx (throat). The pharynx is the hollow tube inside the neck that...
• PharynxThe hollow, muscular tube inside the neck that starts behind the nose and opens into the larynx and...
• Phase 1 clinical trialThe first step in testing a new treatment in humans. A phase 1 clinical trial tests the safety, side effects...
• Phase 1/phase 2 clinical trialA study that tests the safety, side effects, and best dose of a new treatment. Phase 1/phase 2 clinical...
• Phase 2 clinical trialA study that tests whether a new treatment works for a certain type of cancer or other disease (for example...
• Phase 2/phase 3 clinical trialA study that tests how well a new treatment works for a certain type of cancer or other disease and compares...
• Phase 3 clinical trialA study that tests the safety and how well a new treatment works compared with a standard treatment. For...
• Phase 4 clinical trialA type of clinical trial that studies the side effects caused over time by a new treatment after it has been...
• Phase I clinical trialThe first step in testing a new treatment in humans. A phase I clinical trial tests the safety, side effects...
• Phase I detoxificationA process in which the liver uses one of two major enzyme pathways to change a toxic substance, such as an...
• Phase II clinical trialA study that tests whether a new treatment works for a certain type of cancer or other disease (for example...
• Phase II detoxificationA process in which the liver uses one of two major enzyme pathways to change a toxic substance, such as an...
• Phase I/II clinical trialA study that tests the safety, side effects, and best dose of a new treatment. Phase I/II clinical trials...
• Phase III clinical trialA study that tests the safety and how well a new treatment works compared with a standard treatment. For...
• Phase II/III clinical trialA study that tests how well a new treatment works for a certain type of cancer or other disease and compares...
• Phase IV clinical trialA type of clinical trial that studies the side effects caused over time by a new treatment after it has been...
• Phellodendron amurense bark extractA proprietary formulation consisting of a Phellodendron amurense (Amur cork tree) bark extract, often used in...
• Phenelzine sulfateA hydrazine derivative and a potent non-selective monoamine oxidase (MAO) inhibitor with anxiolytic and...
• Phenethyl isothiocyanateA substance being studied in the prevention of cancer. It is a naturally occurring compound found in some...
• Phenethyl isothiocyanate-containing watercress juiceA juice extracted from watercress containing high amounts of phenethyl isothiocyanate (PEITC), with potential...
• Phenformin hydrochlorideThe hydrochloride salt form of phenformin, an agent belonging to the biguanide class of antidiabetics with...
• PhenobarbitalA drug that is used to treat seizures and as a sedative. It is being studied in the treatment of diarrhea and...
• PhenocopyA phenotypic trait or disease that resembles the trait expressed by a particular genotype but in an...
• PhenolA very poisonous chemical substance made from tar and also found in some plants and essential oils (scented...
• PhenothiazineA type of drug that is used to treat severe mental and emotional disorders, severe nausea and vomiting, and...
• PhenotypeThe physical, biochemical, and behavioral traits that can be observed in a person. Some examples of a...
• PhenoxodiolA substance that is being studied in the treatment of cancer. It belongs to the family of drugs called signal...
• Phenoxybenzamine hydrochlorideThe hydrochloride salt form of phenoxybenzamine, a synthetic, dibenzamine alpha-adrenergic antagonist with...
• PhenprocoumonAn orally available, long-acting derivative of coumarin with anticoagulant activity. Upon administration...
• Phentolamine mesylateThe mesylate salt of a synthetic imidazoline with alpha-adrenergic antagonist activity. As a competitive...
• PhenylacetateA substance that is being studied in the treatment of cancer.
• PhenylbutyrateA substance that is being studied in the treatment of cancer. It belongs to the family of drugs called...
• PhenylketonuriaAn inherited disorder that causes a build-up of a substance called phenylalanine in the blood and other body...
• Phenytoin sodiumA drug used to treat or prevent seizures or convulsions that may be caused by epilepsy, brain surgery, or...
• PheochromocytomaTumor that forms in the center of the adrenal gland (gland located above the kidney) that causes it to make...
• PheresisA process in which a machine removes blood stem cells or other parts of the blood from a person’s bloodstream...
• PhesgoA combination of pertuzumab, trastuzumab, and hyaluronidase used with other drugs to treat adults with...
• Philadelphia chromosomeAn abnormal version of chromosome 22 that contains a fusion of two genes, the ABL1 gene and the BCR gene...
• Philadelphia chromosome positiveDescribes cancer cells that have an abnormal chromosome called the Philadelphia (Ph) chromosome. The Ph...
• PhilosophicalHaving to do with the deeper questions of life and with a person’s basic beliefs, ideas, and attitudes.
• PhlebitisInflammation (redness, swelling, pain, and heat) of a vein, usually in the legs. Phlebitis may be caused by...
• PhlebotomyA procedure in which a needle is used to take blood from a vein, usually for laboratory testing. Phlebotomy...
• PhlegmA more than normal amount of thick mucus made by the cells lining the upper airways and lungs. A buildup of...
• pH-low insertion peptide-indocyanine greenAn imaging agent composed of a pH-low insertion peptide (pHLIP) probe coupled with the near-infrared (NIR)...
• PhobiaAn extreme, irrational, fear of something that may cause a person to panic. Examples of common phobias...
• PhosphateA form of phosphoric acid, which contains phosphorus. In the body, phosphates are found in the bones and...
• Phosphatidylcholine-bound silybinAn oral preparation of the flavonoid silybin with potential antioxidant and chemopreventive activities...
• phosphatidylinositol-3 kinaseA type of enzyme that transmits signals in cells and that helps control cell growth. Some tumors have...
• PhospholipidA lipid (fat) that contains phosphorus. Phospholipids are a major part of cell membranes.
• Phospholipid complexA chemical or drug that is attached to a lipid (fat) that contains phosphorus.
• Phosphonoformate trisodiumA drug used to treat infections with herpesviruses in people whose immune systems are weakened by AIDS. It...
• PhosphoricHaving to do with or containing the element phosphorus.
• Phosphoric acidAn acid that contains phosphorus and is used in medicine and dentistry. It is also used to remove rust. A...
• Phosphorodiamidate morpholino oligomer AVI-4126A c-Myc antisense phosphorodiamidate morpholino oligomer (PMO) with potential antineoplastic activity...
• PhosphorusA nonmetallic element that is found in the blood, muscles, nerves, bones, and teeth and is a component of...
• Phosphorus P 32A radioactive form of the element phosphorus. It is used in the laboratory to label DNA and proteins. It has...
• Phosphorus P32A radioactive isotope of phosphorus with beta particle-emitting radiocytotoxic activity. Emitted by...
• PhosphorylationA process in which a phosphate group is added to a molecule, such as a sugar or a protein.
• PhotoactivityThe effect produced when certain substances are exposed to light. In cancer treatment, some drugs become...
• PhotocoagulationThe use of an intense beam of light, such as a laser, to seal off blood vessels or destroy tissue. It is used...
• PhotocyanineA metal complex compound of phthalocyanide with photosensitizing activity. Upon injection with photocyanide...
• Photodynamic compound TLD-1433A non-toxic ruthenium-based coordination-complex and photosensitizer, with potential antineoplastic activity...
• Photodynamic therapyTreatment with drugs that become active when exposed to light. These activated drugs may kill cancer cells.
• PhotofrinA drug used to treat some types of cancer. When absorbed by cancer cells and exposed to light, Photofrin...
• Photon beam radiation therapyA type of radiation therapy that uses x-rays or gamma rays that come from a special machine called a linear...
• PhotopheresisA procedure in which blood is removed from the body and treated with ultraviolet light and drugs that become...
• PhotophobiaA condition in which the eyes are more sensitive than normal to light.
• PhotosensitivityA condition in which the skin becomes very sensitive to sunlight or other forms of ultraviolet light and may...
• PhotosensitizerA drug used in photodynamic therapy. When absorbed by cancer cells and exposed to light, the drug becomes...
• Photosensitizer agent REM-001A second-generation photodynamic therapy (PDT)-based agent, with potential antineoplastic activity upon PDT...
• Photosensitizer LUZ 11A bacteriochlorin-based photosensitizer, with antineoplastic activity upon photodynamic therapy (PDT)...
• Photosensitizing agentA drug used in photodynamic therapy. When absorbed by cancer cells and exposed to light, the drug becomes...
• PhotosynthesisA chemical process that occurs in plants, algae, and some types of bacteria, when they are exposed to...
• PhototestingSpecial tests used to measure the reaction of the skin to ultraviolet radiation. Phototesting is being used...
• PhototherapyThe treatment of disease with certain types of light. Phototherapy can use lasers, LED, fluorescent lamps...
• PhototoxicityA condition in which the skin or eyes become very sensitive to sunlight or other forms of light. It can be...
• PHPA rare condition in which the pituitary gland stops making most or all hormones. Pituitary hormones help...
• PHRA collection of information about a person’s health that allows the person to manage and track his or her own...
• Phrenic nerveA nerve that runs from the spinal cord to the diaphragm (the thin muscle below the lungs and heart that...
• PHTSA group of inherited disorders caused by mutations (changes) in the PTEN gene. In people with PHTS, many...
• Phyllodes tumorA rare tumor that usually forms in the connective tissue of the breast. Phyllodes tumors tend to grow quickly...
• PhysiatristA doctor who has special training in physical medicine. Physical medicine is the prevention and treatment of...
• Physical dependenceA condition in which a person takes a drug over time, and unpleasant physical symptoms occur if the drug is...
• Physical examinationAn exam of the body to check for general signs of disease.
• Physical medicine specialistA doctor who has special training in physical medicine. Physical medicine is the prevention and treatment of...
• Physical therapistA health professional trained to evaluate and treat people who have conditions or injuries that limit their...
• Physical therapyThe use of exercises and physical activities to help condition muscles and restore strength and movement. For...
• Physical touch methodsA type of therapy in which the therapist moves or manipulates one or more parts of the patient’s body. It may...
• PhysicianA person who is trained and licensed to practice medicine. Physicians help prevent, diagnose, treat, and...
• Physician assistantA health professional who is licensed to do certain medical procedures under the guidance of a doctor. A...
• Physician Data QueryPhysician Data Query is an online source of cancer information that is developed and maintained by the...
• PhysiologicHaving to do with the functions of the body. When used in the phrase "physiologic age," it refers to an age...
• Phytic acidA substance found in many foods that come from plants, including corn, wheat, rice, and soybeans, and in...
• PhytochemicalA substance found in plants. Some phytochemicals may reduce the risk of cancer.
• Phytochlorin sodium-polyvinylpyrrolidone complexA photosensitizer composed of the sodium salt form of chlorin e6 and its derivatives complexed with a...
• PhytoestrogenAn estrogen-like substance found in some plants and plant products. Phytoestrogens may have anticancer...
• PhytohemagglutininA substance found in plants that causes red blood cells to clump together and certain white blood cells to...
• PhytolA chemical substance that comes from plants and is used to make vitamins E and K. Phytol is also found in...
• PhytonadioneAn analogue of the naphthoquinone vitamin K found in plants. The vitamins K are essential for blood...
• PhytosterolA plant-based compound that can compete with dietary cholesterol to be absorbed by the intestines, resulting...
• PIThe person(s) in charge of a clinical trial or a scientific research grant. The PI prepares and carries out...
• PI3 kinaseA type of enzyme that transmits signals in cells and that helps control cell growth. Some tumors have...
• PI3KA type of enzyme that transmits signals in cells and that helps control cell growth. Some tumors have...
• PI3K alpha/beta inhibitor BAY1082439An orally bioavailable inhibitor of the class I phosphoinositide 3-kinase (PI3K) alpha and beta isoforms with...
• PI3K alpha/delta inhibitor TQ-B3525An orally available selective inhibitor of the alpha and delta isoforms of phosphatidylinositol 3-kinase...
• PI3K alpha/mTOR inhibitor PWT33597 mesylateThe mesylate salt form of PWT33597, an orally bioavailable dual inhibitor of phosphatidylinositide 3-kinase...
• PI3K delta inhibitor SHC014748MAn orally available selective inhibitor of the delta isoform of phosphatidylinositol 3-kinase (PI3-kinase...
• PI3K inhibitor ACP-319An orally available inhibitor of phosphatidylinositol 3-kinase (PI3K), with potential antineoplastic...
• PI3K inhibitor BGT226A phosphatidylinositol 3-kinase (PI3K) inhibitor with potential antineoplastic activity. PI3K inhibitor...
• PI3K inhibitor GDC-0941 bismesylateThe orally bioavailable bismesylate salt of a potent small-molecule thieno[3,2-d]pyrimidine inhibitor of the...
• PI3K inhibitor GSK1059615A phosphoinositide 3-kinase (PI3K) inhibitor with potential antineoplastic activity. PI3K inhibitor...
• PI3K inhibitor GSK2126458A small-molecule pyridylsulfonamide inhibitor of phosphatidylinositol 3-kinase (PI3K) with potential...
• PI3K inhibitor PX-866A small-molecule wortmannin analogue inhibitor of the alpha, gamma, and delta isoforms of phosphoinositide...
• PI3K inhibitor TL117An orally bioavailable phosphatidylinositol 3-kinase (PI3K) inhibitor, with potential antineoplastic...
• PI3K inhibitor WX-037A phosphatidylinositol 3-kinase (PI3K) inhibitor with potential antineoplastic activity. PI3K inhibitor...
• PI3K inhibitor ZSTK474An orally available, s-triazine derivative, ATP-competitive phosphatidylinositol 3-kinase (PI3K) inhibitor...
• PI3K p110beta/delta inhibitor CVL237A dual selective inhibitor of the beta and delta isoforms of the 110 kDa catalytic subunit of class I...
• PI3Kalpha inhibitor AZD8835An orally bioavailable inhibitor of the class I phosphatidylinositol-4,5-bisphosphate 3-kinase (PI3K)...
• PI3K-alpha inhibitor HS-10352An orally bioavailable, small molecule inhibitor of the class I phosphatidylinositol-4,5-bisphosphate...
• PI3K-alpha inhibitor JS105An orally bioavailable inhibitor of the class I phosphatidylinositol-4,5-bisphosphate 3-kinase (PI3K)...
• PI3K-alpha inhibitor TOS-358An orally bioavailable, covalent inhibitor of class I phosphatidylinositol-4,5-bisphosphate 3-kinase (PI3K)...
• PI3Ka/mTOR inhibitor PKI-179A second generation, small-molecule mimetic of ATP that targets the mammalian target of rapamycin (mTOR) with...
• PI3Kbeta inhibitor AZD8186An inhibitor of the beta isoform of phosphoinositide-3 kinase (PI3K), with potential antineoplastic activity...
• PI3K-beta inhibitor GSK2636771An orally bioavailable, substituted benzimidazole inhibitor of the class I phosphoinositide 3-kinase (PI3K)...
• PI3K-beta Inhibitor SAR260301An orally bioavailable inhibitor of the class I phosphatidylinositol 3-kinase (PI3K) beta isoform with...
• PI3K-delta inhibitor AMG 319A highly selective, potent, and orally bioavailable small molecule inhibitor of the delta isoform of the 110...
• PI3K-delta inhibitor BGB-10188An orally available selective inhibitor of the delta isoform of phosphatidylinositol 3-kinase (PI3-kinase...
• PI3Kdelta inhibitor GS-9901An orally bioavailable, small molecule inhibitor of the delta isoform of phosphoinositide-3 kinase...
• PI3Kdelta inhibitor INCB040093An orally bioavailable, selective inhibitor of the delta isoform of the 110 kDa catalytic subunit of class I...
• PI3Kdelta/gamma inhibitor ZX-101AAn orally bioavailable inhibitor of the delta and gamma isoforms of phosphoinositide-3 kinase (PI3K), with...
• PI3K-gamma inhibitor HS248An orally bioavailable selective inhibitor of the gamma isoform of phosphoinositide-3 kinase (PI3Kg), with...
• PI3K-gamma inhibitor IPI-549An orally bioavailable, highly selective small molecule inhibitor of the gamma isoform of phosphoinositide-3...
• PI3K-gamma inhibitor ZX-4081An orally bioavailable selective inhibitor of the gamma isoform of phosphoinositide-3 kinase (PI3Kg), with...
• PI3K/mTOR dual kinase inhibitor XL765An orally bioavailable small molecule targeting the phosphatidylinositol 3 kinase (PI3K) and mammalian target...
• PI3K/mTOR inhibitor CLL442A topical inhibitor of class I phosphoinositide 3-kinase (PI3K) isoforms and mammalian target of rapamycin...
• PI3K/mTOR inhibitor HEC 68498An orally bioavailable, small molecule inhibitor of class I phosphoinositide 3-kinase (PI3K) isoforms and...
• PI3K/mTOR inhibitor LY3023414An orally bioavailable, small molecule inhibitor of certain class I phosphoinositide 3-kinase (PI3K) isoforms...
• PI3K/mTOR kinase inhibitor DS-7423An orally bioavailable inhibitor of phosphatidylinositol 3 kinase (PI3K) and mammalian target of rapamycin...
• PI3K/mTOR kinase inhibitor PF-04691502An agent targeting the phosphatidylinositol 3 kinase (PI3K) and mammalian target of rapamycin (mTOR) in the...
• PI3K/mTOR kinase inhibitor VS-5584A potent and selective inhibitor of both phosphatidylinositol 3 kinase (PI3K) and mammalian target of...
• PI3K/mTOR kinase inhibitor WXFL10030390An orally bioavailable, small molecule inhibitor of certain phosphoinositide 3-kinase (PI3K) isoforms and...
• PI3K/mTOR/ALK-1/DNA-PK inhibitor P7170An orally bioavailable inhibitor of phosphoinositide 3-kinase (PI3K), mammalian target of rapamycin (mTOR)...
• PI3K/mTORC1/mTORC2 inhibitor DCBCI0901An inhibitor of phosphatidylinositide 3-kinase (PI3K), raptor-mTOR (mTOR complex 1 or mTORC1) and rictor-mTOR...
• PI-88A substance that is being studied in the treatment of cancer. It belongs to the family of drugs called...
• PibenzimolA fluorescent dye of benzimidazole derivative. Pibenzimol binds to AT-specific sites in the minor groove of...
• PibrozelesinA semisynthetic water-soluble derivative of the antineoplastic antibiotic duocarmycin B2. Activated by...
• PicatoA drug applied to the skin to treat actinic keratosis (thick, scaly growths on the skin that may become...
• PICCA device used to draw blood and give treatments, including intravenous fluids, drugs, or blood transfusions...
• PicibanilA lyophilized formulation containing cultures of a low-virulent strain of Streptococcus pyogenes, treated and...
• PicoplatinA new generation organic platinum analog with an extended spectrum of antineoplastic activity. Designed to...
• PicropodophyllinA cyclolignan alkaloid found in the mayapple plant family (Podophyllum peltatum), and a small molecule...
• PIDA condition in which the female reproductive organs are inflamed. It may affect the uterus, fallopian tubes...
• PidilizumabA humanized, immunoglobulin (Ig) G1 monoclonal antibody directed against human inhibitory receptor programmed...
• PidnarulexAn orally bioavailable inhibitor of RNA polymerase I (Pol I), with potential antineoplastic activity. Upon...
• PigmentA substance that gives color to tissue. Pigments are responsible for the color of skin, eyes, and hair.
• PIK3CA geneA gene that makes one of the proteins in an enzyme called PI3K, which is involved in many important functions...
• PilocarpineA drug used to increase salivation in people who have dry mouth caused by opioids or radiation therapy...
• Pilocarpine hydrochlorideThe hydrochloride salt of a natural alkaloid extracted from plants of the genus Pilocarpus with cholinergic...
• PilocyticMade up of cells that look like fibers when viewed under a microscope.
• Pilot studyThe initial study examining a new method or treatment.
• PIM kinase inhibitor LGH447An orally available pan-PIM protein kinase inhibitor with potential antineoplastic activity. PIM kinase...
• Pim kinase inhibitor SGI-1776A small-molecule pan-Pim protein kinase inhibitor with potential antineoplastic activity. Pim kinase...
• PIM kinase inhibitor TP-3654An orally available, second-generation and selective ATP-competitive inhibitor of proviral integration site...
• PimasertibAn orally bioavailable small-molecule inhibitor of MEK1 and MEK2 (MEK1/2) with potential antineoplastic...
• Pimasertib hydrochlorideThe hydrochloride salt form of pimasertib, an orally bioavailable small-molecule inhibitor of mitogen...
• Pimecrolimus creamA 33-epi-chloro-derivative of the ascomycin macrolactam with immunosuppressant properties. Pimecrolimus binds...
• PimicotinibAn orally bioavailable inhibitor of colony stimulating factor 1 receptor (CSF1R; CSF-1R; CD115; M-CSFR), with...
• PimitespibA specific inhibitor of heat shock protein 90 (Hsp90) subtypes alpha and beta, with potential antineoplastic...
• PimodivirAn orally bioavailable non-nucleoside inhibitor of the polymerase basic protein 2 (PB2) subunit of the...
• PimonidazoleA nitroimidazole with hypoxic selectivity and radiosensitizing property. Pimonidazole is reduced in hypoxic...
• Pimonidazole hydrochlorideA substituted nitroimidazole salt. Hypoxic cells bioreductively activate and bind pimonidazole. This agent...
• PimurutamabA glycoengineered humanized version of the monoclonal antibody of cetuximab, with potential antineoplastic...
• PINNoncancerous growth of cells lining the internal and external surfaces of the prostate gland. Having...
• Pinaverium bromideAn orally available bromide salt form of pinaverium, a calcium channel blocker (CCB) with antispasmodic...
• Pineal bodyA tiny organ in the cerebrum that produces melatonin. Also called pineal gland and pineal organ.
• Pineal germinomaA type of germ cell tumor that is found in the pineal gland in the brain. Symptoms of pineal germinomas...
• Pineal glandA tiny organ in the cerebrum that produces melatonin. Also called pineal body and pineal organ.
• Pineal organA tiny organ in the cerebrum that produces melatonin. Also called pineal body and pineal gland.
• Pineal region tumorA type of brain tumor that forms in or around the pineal gland (a tiny organ near the center of the brain)...
• PinealomaA type of brain tumor that forms in or around the pineal gland (a tiny organ near the center of the brain)...
• PineoblastomaA fast growing type of brain tumor that occurs in or around the pineal gland, a tiny organ near the center of...
• PineocytomaA slow growing type of brain tumor that occurs in or around the pineal gland, a tiny organ near the center of...
• PinkeyeA condition in which the conjunctiva (membranes lining the eyelids and covering the white part of the eye)...
• PinometostatAA small molecule inhibitor of histone methyltransferase with potential antineoplastic activity. Upon...
• PioglitazoneA drug that is used to treat type 2 diabetes and is being studied in the prevention of head and neck cancer...
• Pioglitazone hydrochlorideThe hydrochloride salt of an orally-active thiazolidinedione with antidiabetic properties and potential...
• PipeAs it relates to tobacco use, a device that has a mouthpiece at one end of a tube and a small bowl at the...
• PipendoxifeneA nonsteroidal 2-phenyl indole and a selective estrogen receptor modulator (SERM) with potential...
• Piperacillin sodiumThe sodium salt of piperacillin, a broad-spectrum semisynthetic, ampicillin-derived ureidopenicillin...
• Piperacillin-tazobactamA drug combination that is used to treat infection in people with cancer. Piperacillin is a synthetic...
• PiperazinedioneA crystalline antibiotic fermentation product isolated from the bacterium Streptomyces griseoluteus with...
• Piperine extract (standardized)A standardized extract containing the active alkaloid piperine, derived from the fruit of the plant Piper...
• PiqrayA drug used with fulvestrant to treat postmenopausal women, and men, with hormone-receptor positive...
• PirarubicinAn analogue of the anthracycline antineoplastic antibiotic doxorubicin. Pirarubicin intercalates into DNA and...
• PirfenidoneA substance that is being studied in the prevention and treatment of scar tissue caused by radiation therapy...
• PiritramideA diphenylpropylamine and opioid receptor agonist, with analgesic activity. Upon administration, piritramide...
• PiritreximA substance that is being studied in the treatment of cancer. It belongs to the family of drugs called folate...
• PirotinibAn orally bioavailable inhibitor of the receptor tyrosine kinase (RTK) epidermal growth factor receptor...
• PiroxantroneAn anthrapyrazole antineoplastic antibiotic. Piroxantrone intercalates into DNA and interacts with...
• PiroxicamA nonsteroidal oxicam derivative with anti-inflammatory, antipyretic and analgesic properties. As a...
• pIRS2 phosphopeptide-tetanus peptide vaccineA vaccine composed of a phosphorylated peptide from the tumor associated antigen insulin receptor substrate-2...
• PirtobrutinibA drug used to treat adults with chronic lymphocytic leukemia, small lymphocytic lymphoma, or mantle cell...
• Pitavastatin calciumA calcium salt formulation of pitavastatin, a novel statin that induces plaque regression and elevates...
• Pituitary glandA pea-sized organ attached to the part of the brain called the hypothalamus. It lies at the base of the brain...
• Pituitary tumorA tumor that forms in the pituitary gland. The pituitary gland is a pea-sized organ at the base of the brain...
• PixantroneA substance that is being studied in the treatment of cancer. It belongs to the family of drugs called...
• Pixantrone dimaleateThe dimaleate salt of a synthetic, noncardiotoxic aza-anthracenedione analogue with potential antineoplastic...
• PixatimodA synthetic sugar modified heparan sulfate mimetic and agonist of toll-like receptor 9 (TLR9), with potential...
• PJSA rare genetic disorder in which many polyps (abnormal growths of tissue) form in the lining of the...
• PKCAn enzyme found throughout the body's tissues and organs. Several forms of PKC are involved in many cellular...
• PKC412A drug used alone or with other anticancer drugs to treat adults with certain types of acute myeloid...
• PKC-beta inhibitor MS-553An orally available inhibitor of the beta-isoform of protein kinase C (PKC), with potential immunosuppressive...
• PKMYT1 inhibitor XL495An orally bioavailable small molecule inhibitor of the human membrane-associated tyrosine- and...
• PK-R allosteric activator AG-348An orally available, small-molecule, allosteric activator of the red cell isoform of pyruvate kinase (PK-R)...
• PKUAn inherited disorder that causes a build-up of a substance called phenylalanine in the blood and other body...
• PlaceboAn inactive substance or other intervention that looks the same as, and is given the same way as, an active...
• Placebo therapyAn inactive treatment that is designed to mimic as closely as possible the active treatment being studied in...
• Placebo-controlledRefers to a clinical study in which the control patients receive a placebo.
• PlacentaThe organ that nourishes the developing fetus in the uterus.
• Placental blood transplantationThe transfer of blood from a placenta to an individual whose own blood production system is suppressed...
• Pladienolide derivative E7107A synthetic urethane derivative of pladienolide D with potential antineoplastic activity. Pladienolide...
• PlamotamabA bispecific, Fc domain-containing, monoclonal antibody with potential antineoplastic activity. Plamotamab...
• Plan BA form of the hormone progesterone that is made in the laboratory and used to prevent pregnancy. It is being...
• Plant sterolA plant-based compound that can compete with dietary cholesterol to be absorbed by the intestines, resulting...
• Plantar pitA tiny dent in the skin on the bottom (sole) of the foot. Plantar pits are usually pink or skin-colored and...
• Plant-derived hematopoiesis enhancer PG2A proprietary botanical formulation derived from a traditional Chinese medicinal (TCM) plant with...
• PlaqueIn medicine, a small, abnormal patch of tissue on a body part or an organ. Plaques may also be a build-up of...
• Plaque radiotherapyA type of radiation therapy used to treat eye tumors. A thin piece of metal (usually gold) with radioactive...
• PlasmaThe clear, yellowish, fluid part of the blood that carries the blood cells. The proteins that form blood...
• Plasma cellA type of immune cell that makes large amounts of a specific antibody. Plasma cells develop from B cells that...
• Plasma cell myelomaA type of cancer that begins in plasma cells (white blood cells that produce antibodies). Also called Kahler...
• Plasma cell neoplasmA type of tumor that begins in plasma cells (white blood cells that make antibodies). Multiple myeloma...
• Plasma cell tumorA type of tumor that begins in plasma cells (white blood cells that make antibodies). Multiple myeloma...
• Plasma exchangeA procedure in which a machine is used to separate the plasma (the liquid part of the blood) from the blood...
• Plasma membraneThe outer membrane of a cell.
• Plasmablastic lymphomaA very aggressive (fast-growing) type of large B-cell non-Hodgkin lymphoma (cancer that begins in the cells...
• PlasmacyteA type of immune cell that makes large amounts of a specific antibody. Plasmacytes develop from B cells that...
• PlasmacyticHaving to do with plasma cells (a type of white blood cells).
• Plasmacytoid dendritic cell vaccineA whole cell vaccine derived from a distinct subset of dendritic cells (DCs) with a plasma cell-like...
• PlasmacytomaA type of cancer that begins in plasma cells (white blood cells that produce antibodies). A plasmacytoma may...
• PlasmapheresisA procedure in which a machine is used to separate the plasma (the liquid part of the blood) from the blood...
• Plasmid DNA vaccine pING-hHER3FLA plasmid DNA cancer vaccine encoding the tumor-associated antigen (TAA) human epidermal growth factor...
• Plasmid encoding antiangiogenic metargidin peptideA plasmid encoding the protein antiangiogenic metargidin plasmid (AMEP), the disintegrin domain of ADAM-15...
• Plasmodium vivaxA protozoan parasite in the family Plasmodiidae. P. vivax is the most frequent and widely distributed...
• Plasmodium vivax-infected red blood cellsA preparation of red blood cells (RBCs) that have been infected with the malaria parasite Plasmodium vivax...
• Plastic surgeonA surgeon who has special training in reducing scarring or disfigurement that may occur as a result of...
• Plastic surgeryAn operation that restores or improves the appearance of body structures.
• PlateletA tiny, disc-shaped piece of cell that is found in the blood and spleen. Platelets are pieces of very large...
• Platelet-derived growth factorA family of molecules released from platelets (tiny pieces of cells that are found in the blood and that help...
• Platelet-derived growth factor receptor alpha geneA gene that makes a protein that is involved in cell division and cell survival. Mutated (changed) forms of...
• Platelet-rich plasmaAn autologous preparation of platelet-rich plasma (PRP) that may potentially be used to treat fecal...
• PlatinolA drug that contains the active ingredient cisplatin, which is used to treat certain types of bladder cancer...
• PlatinumA metal that is an important component of some anticancer drugs, such as cisplatin and carboplatin.
• Platinum acetylacetonate-titanium dioxide nanoparticlesA preparation of platinum acetylacetonate supported by sol-gel technology functionalized titania, with...
• Platinum refractory cancerCancer that does not respond to treatment with anticancer drugs that contain the metal platinum, such as...
• Platinum resistant cancerCancer that responds at first to treatment with drugs that contain the metal platinum, such as cisplatin and...
• Platinum sensitive cancerCancer that responds to treatment with anticancer drugs that contain the metal platinum, such as cisplatin...
• PLCISA condition in which abnormal cells are found in the lobules (milk glands) of the breast. The cells tend to...
• PlecanatideAn agonist of intestinal guanylate cyclase type C (GC-C) which is almost structurally identical to human...
• Plectin-1 targeting agent PTP-01An imaging agent containing a plectin-1 (Plec1; plectin) targeting peptide (PTP), with potential use for the...
• PLED-based MnSOD mimeticA derivative of pyridoxyl ethyldiamine (PLED) and mimetic of the human mitochondrial manganese superoxide...
• PlenaxisA drug used to reduce the amount of testosterone made in patients with advanced symptomatic prostate cancer...
• PleomorphicOccurring in various distinct forms. In terms of cells, having variation in the size and shape of cells or...
• Pleomorphic liposarcomaA rare, fast-growing type of cancer that begins in fat cells. It usually forms in the deep soft tissues of...
• Pleomorphic lobular carcinoma in situA condition in which abnormal cells are found in the lobules (milk glands) of the breast. The cells tend to...
• PlerixaforA drug used with granulocyte colony-stimulating factor before an autologous stem cell transplant in patients...
• PleuraA thin layer of tissue that covers the lungs and lines the interior wall of the chest cavity. It protects and...
• Pleural cavityThe space enclosed by the pleura, which is a thin layer of tissue that covers the lungs and lines the...
• Pleural effusionAn abnormal collection of fluid between the thin layers of tissue (pleura) lining the lung and the wall of...
• PleurectomySurgery to remove part of the pleura (a thin layer of tissue that covers the interior wall of the chest...
• PleurodesisA medical procedure that uses chemicals or drugs to cause inflammation and adhesion between the layers of the...
• Pleuropulmonary blastomaA rare, fast-growing cancer that forms in the tissues of the lung and pleura (the thin layer of tissue that...
• Pleuropulmonary blastoma familial cancer syndromeA rare, inherited disorder that increases the risk of pleuropulmonary blastoma (a rare, fast-growing cancer...
• PlevitrexedAn orally bioavailable, small molecule, non-polyglutamatable, antifolate quinazoline derivative thymidine...
• Plexiform fibrohistiocytic tumorA rare tumor found mainly in children and young adults. It usually forms in the skin on the arms and legs. It...
• Plexiform neurofibromaA tumor that forms in the tissue that covers and protects the nerves. Plexiform neurofibromas can occur...
• PlexopathyA disorder affecting a network of nerves, blood vessels, or lymph vessels.
• PlicamycinA drug used to treat some types of testicular cancer. It is also used to treat a higher-than-normal amounts...
• PlinabulinAn orally active diketopiperazine derivative with potential antineoplastic activity. Plinabulin selectively...
• PlitidepsinA cyclic depsipeptide isolated from the marine tunicate Aplidium albicans. Plitidepsin displays a broad...
• PlixorafenibAn orally bioavailable inhibitor and specific dimer breaker of the serine/threonine-protein kinase B-raf...
• PLK1 inhibitor CYC140A competitive inhibitor for adenosine triphosphate (ATP) binding to polo-like kinase 1 (PLK1; PLK-1; STPK13)...
• PLK1 inhibitor TAK-960An orally available, Polo-like kinase 1 (PLK1) inhibitor with potential antineoplastic activity. Polo-like...
• PLK4 inhibitor RP-1664An orally bioavailable inhibitor of polo-like kinase 4 (PLK4), with potential antineoplastic activity. Upon...
• PLLA type of chronic lymphocytic leukemia (CLL) in which too many immature white blood cells (prolymphocytes)...
• PloidyThe number of sets of chromosomes in a cell or an organism. For example, haploid means one set and diploid...
• PlozalizumabA humanized monoclonal antibody directed against the human chemokine receptor 2 (CCR2), with potential...
• Plummer-Vinson syndromeA disorder marked by anemia caused by iron deficiency, and a web-like growth of membranes in the throat that...
• PluripotentAble to mature or develop in any of several ways.
• Pluripotent stem cellA cell that is able to develop into many different types of cells or tissues in the body.
• PluvictoA radioactive drug used to treat adults with PSMA-positive prostate cancer that has spread to other parts of...
• PLX4032A drug used to treat Erdheim-Chester disease (a very rare type of histiocytosis) and advanced melanoma that...
• PLZ4-coated paclitaxel-loaded micelle formulationA nanoparticle-based formulation consisting of polymeric micelles encapsulating the taxane paclitaxel that...
• PM00104A synthetic tetrahydroisoquinoline alkaloid related to the marine natural compounds Jorumycin and the family...
• pM-81A monoclonal antibody that is being studied in the detection and treatment of cancer. Monoclonal antibodies...
• PML geneA gene that makes a protein that helps control cell growth and cell division. Mutations (changes) in the PML...
• PMNA type of immune cell that has granules (small particles) with enzymes that are released during infections...
• PN401A drug used in the emergency treatment of adults and children who receive too much fluorouracil or...
• PNAA type of anticancer drug that is similar to a natural chemical compound called purine. Cells use purine to...
• PNETOne of a group of cancers that develop from the same type of early cells, and share certain biochemical and...
• Pneumatic larynxA device that is used to help a person talk after a laryngectomy. It uses air to produce a humming sound...
• Pneumococcal 13-valent conjugate vaccineA pneumococcal conjugate vaccine containing 13 different strains of the bacterium Streptococcus pneumoniae...
• Pneumococcal 20-valent conjugate vaccineA pneumococcal conjugate vaccine containing 20 different strains of the bacterium Streptococcus pneumoniae...
• Pneumococcal 7-valent conjugate vaccineAn active immunizing agent used to prevent infection by the bacterium Streptococcus pneumoniae. Pneumococcal...
• Pneumococcal polyvalent vaccineAn polyvalent vaccine used to prevent infection by the bacterium Streptococcus pneumoniae. Pneumococcal...
• PneumonectomySurgery to remove all of one lung. In a partial pneumonectomy, one or more lobes of a lung are removed.
• PneumoniaA severe inflammation of the lungs in which the alveoli (tiny air sacs) are filled with fluid. This may cause...
• PneumonitisInflammation of the lungs. This may be caused by disease, infection, radiation therapy, allergy, or...
• PneumothoraxAn abnormal collection of air in the space between the thin layer of tissue that covers the lungs and the...
• pNGVL3-hICD vaccineA plasmid DNA cancer vaccine encoding the intracellular domain (ICD) of the HER-2/neu proto-oncogene. Upon...
• pNGVL3-hICD vaccine AST-301A plasmid DNA therapeutic cancer vaccine encoding the intracellular domain (ICD) of the HER-2/neu...
• pNGVL4a-CRT-E6E7L2 DNA vaccineA therapeutic DNA vaccine encoding human calreticulin (CRT) linked to human papillomavirus (HPV) type 16 E6...
• pNGVL4a-CRT/E7(detox) DNA vaccineA cancer vaccine consisting of the DNA plasmid pNGVL4a-A encoding calreticulin (CRT) linked to a detox form...
• pNGVL4a-Sig/E7(detox)/HSP70 DNA and HPV16 L2/E6/E7 fusion protein TA-CIN vaccine PVX-2A cancer vaccine consisting of a combination of two vaccines, a prime pNGVL4a-Sig/E7(detox)/HSP70 DNA vaccine...
• pNGVL4a-Sig/E7(detox)/HSP70 DNA vaccineAn antigen-specific DNA cancer vaccine consisting of the coding sequences of a signal peptide (pNGVL4a-Sig)...
• PNHParoxysmal nocturnal hemoglobinuria. A rare disorder in which red blood cells are easily destroyed by certain...
• PNP-expressing ovine atadenovirus FP253An ovine atadenovirus encoding E. coli purine nucleoside phosphorylase (PNP) with prodrug activating...
• PNU 166148A substance that is being studied in the treatment of cancer. It belongs to the family of drugs called...
• PNU-93914A form of the anticancer drug paclitaxel that is contained in very tiny, fat-like particles. It may have...
• PodiatristA doctor who has special training in diagnosing and treating foot and ankle problems.
• PoikilodermaIrregular patterns of reddish brown pigmentation of the skin associated with sun exposure, aging, or a...
• Poikiloderma congenitaleA rare, inherited disorder that affects many parts of the body, especially the skin, eyes, bones, hair, and...
• Point mutationA genetic alteration caused by the substitution of a single nucleotide for another nucleotide. Also called...
• Point variantA genetic alteration caused by the substitution of a single nucleotide for another nucleotide. Also called...
• Pol theta inhibitor ART4215An orally bioavailable and selective inhibitor of DNA polymerase (pol) theta, with potential chemosensitizing...
• PolaprezincAn orally bioavailable chelate composed of zinc and L-carnosine, with potential gastroprotective...
• Polatuzumab vedotinA drug used with other drugs to treat adults with certain types of diffuse large B-cell lymphoma. It is also...
• Polatuzumab vedotin-piiqAn antibody-drug conjugate (ADC) composed of a monoclonal antibody directed against B-cell antigen receptor...
• PolfermetinibAn orally bioavailable, brain penetrating inhibitor of mitogen-activated protein kinase kinase (MAP2K; MAPKK...
• POLH geneA gene that makes a protein involved in copying DNA before a cell divides and in repairing damaged DNA...
• PolidocanolAn alkyl polyglycol ether of lauryl alcohol with sclerosing and potential antineoplastic activities. Upon...
• Polifeprosan 20 carmustine implantA drug used with surgery and radiation therapy to treat high-grade glioma that has not already been treated...
• PoliglusamA naturally occurring polysaccharide composed of beta-1,4-linked glucosamine residues with potential...
• Polihexanide solutionA solution containing the polymer polihexanide, with potential antimicrobial, disinfectant and wound healing...
• PolivyA drug used with other drugs to treat adults with certain types of diffuse large B-cell lymphoma. It is also...
• Pollen extract PCC-100A pollen extract with potential use in the management of certain vasomotor symptoms of menopause. Upon...
• Polo-like kinase 1 inhibitor GSK-461364A small molecule Polo-like kinase 1 (PLK1) inhibitor with potential antineoplastic activity. Polo-like kinase...
• Polo-like kinase 1 inhibitor MK1496An orally bioavailable Polo-like kinase 1 (Plk1) inhibitor with potential antineoplastic activity. Polo-like...
• Polo-like kinase 1 inhibitor NMS-1286937An orally bioavailable, small-molecule Polo-like kinase 1 (PLK1) inhibitor with potential antineoplastic...
• Poly (ADP-ribose) polymeraseA type of enzyme involved in many functions of the cell, including the repair of DNA damage. DNA damage may...
• Poly (ADP-ribose) polymerase inhibitorA substance that blocks an enzyme in cells called PARP. PARP helps repair DNA when it becomes damaged. DNA...
• Poly (ADP-ribose) polymerase-1An enzyme involved in many functions of the cell, including the repair of DNA damage. DNA damage may be...
• Poly AUA synthetic polyadenylic-polyuridylic acid double-stranded RNA. Poly AU may stimulate the release of...
• Poly ICA synthetic polyinosinic-polycytidylic acid double-stranded RNA. Poly IC may stimulate the release of...
• Polyacrylamide hydrogelA transparent, biocompatible, non-resorbable, homogenous hydrogel containing 97.5% apyrogenic water and 2.5%...
• Poly-alendronate dextran-guanidine conjugateA polybisphosphonate dextran-guanidine conjugate with potential anti-resorptive and antineoplastic...
• Polyamine analogue PG11047A second generation polyamine analogue, synthesized through the restriction of molecular conformations of...
• Polyamine analogue SBP-101An analogue of naturally occurring polyamine (PA), with potential antineoplastic activity. Upon subcutaneous...
• Polyamine transport inhibitor AMXT-1501 dicaprateThe dicaprate salt form of AMXT-1501, an orally bioavailable polyamine transport inhibitor, with...
• Polycarbophil/carbomer/glycerin/palm oil glyceride/mineral oil-containing vaginal moisturizerA commercial combination preparation that contains an adhesive polycarbophil polymer, which is used for...
• Polychlorinated biphenylOne of a large group of man-made chemical compounds that were used to make many products, including...
• Polycyclic aromatic hydrocarbonA type of chemical formed when coal, oil, gas, garbage, tobacco, meat, and other substances are burned. These...
• Polycystic ovary syndromeA condition marked by infertility, enlarged ovaries, menstrual problems, high levels of male hormones, excess...
• Polycythemia veraA disease in which there are too many red blood cells in the bone marrow and blood, causing the blood to...
• Polyethylene glycolA polymer made by joining molecules of ethylene oxide and water together in a repeating pattern. Polyethylene...
• Polyethylene glycol 1000 cetyl ether creamA cream containing a non-ionic surfactant belonging to the polyethylene glycol (PEG) family. Polyethylene...
• Polyethylene glycol 3350-containing enema NER1008An enema containing the osmotic agent polyethylene glycol (PEG) 3350, also called macrogol 3350, with...
• Polyethylene glycol hydrogelA 2- or 3-dimensional hydrophilic, cross-linked polymer of polyethylene glycol (PEG). These hydrogels can be...
• Polyethylene glycol recombinant endostatinA formulation containing recombinant endostatin attached to polyethylene glycol (PEG), with potential...
• Polyethylene glycosylated recombinant human megakaryocyte growth and development factorA form of megakaryocyte growth and development factor (MGDF) that is made in the laboratory. MGDF comes from...
• polyethyleneglycol-7-ethyl-10-hydroxycamptothecinA polyethylene glycol (PEG) conjugate of 7-ethyl-10-hydroxycamptothecin with potential antineoplastic...
• polyethyleneglycol-7-ethyl-10-hydroxycamptothecin DFP-13318A long-acting formulation composed of 7-ethyl-10-hydroxycamptothecin (SN38), a camptothecin derivative and...
• Poly-gamma glutamic acidA water-soluble and biodegradable polymer naturally synthesized by various strains of Bacillus and composed...
• Polygenic risk scoreAn assessment of the risk of a specific condition based on the collective influence of many genetic variants...
• Polyglutamate camptothecinA form of the anticancer drug camptothecin that may have fewer side effects and work better than...
• poly-ICLCA substance that is being studied in the treatment of cancer and for its ability to stimulate the immune...
• Polyinosinic-polycytidylic acid/inactivated rabies virus vaccine YS-ON-001A cancer vaccine composed of inactivated rabies vaccine (RV-V) and polyinosinic-polycytidylic acid (poly IC...
• PolymerA molecule made up of small identical molecules called monomers. The monomers are joined together in a...
• Polymerase chain reactionA laboratory method used to make many copies of a specific piece of DNA from a sample that contains very tiny...
• Polymer-conjugated IL-15 receptor agonist NKTR-255A long-acting formulation composed of the human cytokine interleukin-15 (IL-15) that is conjugated by...
• Polymer-encapsulated luteolin nanoparticleA nanoparticle formulation containing the poorly water-soluble naturally-occurring flavonoid luteolin...
• Polymeric camptothecin prodrug XMT-1001A polymeric prodrug of camptothecin (CPT) with potential antineoplastic activity. Polymeric camptothecin...
• Polymeric enteral nutrition formulaA nutritional drink that may help people who cannot get everything they need in their diet from foods and...
• Polymeric nanoparticle-conjugated camptothecin DAN-222A polymeric nanoparticle formulation of the topoisomerase I inhibitor camptothecin (CPT), an alkaloid...
• PolymorphismA common change in the genetic code in DNA. Polymorphisms can have a harmful effect, a good effect, or no...
• Polymorphonuclear leukocyteA type of immune cell that has granules (small particles) with enzymes that are released during infections...
• PolymyositisAn inflammatory disease of the muscles closest to the center of the body. It causes weakness, inability to...
• Polymyxin BA mixture of the polypeptides polymyxins B1 and B2, both obtained from Bacillus polymyxa strains, with...
• polymyxin-B immobilized fiber PMX-20RA cartridge containing a polystyrene-based composite woven fiber that is covalently attached to the...
• PolyneuritisInflammation of several peripheral nerves at the same time.
• PolypA growth that protrudes from a mucous membrane.
• PolypectomySurgery to remove a polyp.
• PolypeptideA substance that contains many amino acids (the molecules that join together to form proteins).

1,454 of 17,717 terms in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.