Perillyl alcohol
Term · Oncology and biomedicine · MLC-T-ONC-006514
A substance that is being studied in the prevention of cancer. It belongs to the family of plant drugs called monoterpenes.
A naturally occurring monoterpene related to limonene with antineoplastic activity. Perillyl alcohol inhibits farnesyl transferase and geranylgeranyl transferase, thereby preventing post-translational protein farnesylation and isoprenylation and activation of oncoproteins such as p21-ras, and arresting tumor cells in the G1 phase of the cell cycle.
| Identifier | MLC-T-ONC-006514 |
|---|---|
| Field | Oncology and biomedicine |
| Abbreviation | POH |
| Synonyms | perilla alcohol; dihydrocuminyl alcohol; perillic alcohol; perillol |
| References | NCI Dictionary of Cancer Terms; National Cancer Institute Thesaurus (CC BY 4.0) |
Record as JSON
{
"id": "MLC-T-ONC-006514",
"term": "Perillyl alcohol",
"field": "Oncology and biomedicine",
"definitions": [
"A substance that is being studied in the prevention of cancer. It belongs to the family of plant drugs called monoterpenes.",
"A naturally occurring monoterpene related to limonene with antineoplastic activity. Perillyl alcohol inhibits farnesyl transferase and geranylgeranyl transferase, thereby preventing post-translational protein farnesylation and isoprenylation and activation of oncoproteins such as p21-ras, and arresting tumor cells in the G1 phase of the cell cycle."
],
"abbreviation": "POH",
"synonyms": [
"perilla alcohol",
"dihydrocuminyl alcohol",
"perillic alcohol",
"perillol"
],
"references": [
"NCI Dictionary of Cancer Terms",
"National Cancer Institute Thesaurus"
],
"url": "https://mlchart.com/terminology/oncology/perillyl-alcohol/"
}
Record 12,967 of 17,717 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.