Phase I clinical trial

{
  "id": "MLC-T-ONC-006596",
  "term": "Phase I clinical trial",
  "field": "Oncology and biomedicine",
  "definition": "The first step in testing a new treatment in humans. A phase I clinical trial tests the safety, side effects, best dose, and timing of a new treatment. It may also test the best way to give a new treatment (for example, by mouth, infusion into a vein, or injection) and how the treatment affects the body. The dose is usually increased a little at a time in order to find the highest dose that does not cause harmful side effects. Phase I clinical trials usually include only a small number of patients who have not been helped by other treatments. Sometimes they include healthy volunteers. Also called phase 1 clinical trial.",
  "synonyms": [
    "phase 1 clinical trial"
  ],
  "references": [
    "NCI Dictionary of Cancer Terms"
  ],
  "url": "https://mlchart.com/terminology/oncology/phase-i-clinical-trial/"
}