MLchartDataset catalogue

pNGVL4a-Sig/E7(detox)/HSP70 DNA vaccine

Term · Oncology and biomedicine · MLC-T-ONC-016133

An antigen-specific DNA cancer vaccine consisting of the coding sequences of a signal peptide (pNGVL4a-Sig), a detox form of the human papillomavirus type 16 (HPV-16) antigen E7, and the heat shock protein 70 (HSP70). Upon administration, this vaccine may generate potent cytotoxic CD8(+) T-cell responses against E7-expressing tumor cells, resulting in tumor cell death.

Table 1. Record
IdentifierMLC-T-ONC-016133
FieldOncology and biomedicine
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON 
{
  "id": "MLC-T-ONC-016133",
  "term": "pNGVL4a-Sig/E7(detox)/HSP70 DNA vaccine",
  "field": "Oncology and biomedicine",
  "definition": "An antigen-specific DNA cancer vaccine consisting of the coding sequences of a signal peptide (pNGVL4a-Sig), a detox form of the human papillomavirus type 16 (HPV-16) antigen E7, and the heat shock protein 70 (HSP70). Upon administration, this vaccine may generate potent cytotoxic CD8(+) T-cell responses against E7-expressing tumor cells, resulting in tumor cell death.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/pngvl4a-sig-e7-detox-hsp70-dna-vaccine/"
}

Record 13,397 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.