neoantigen-HSP70 peptide cancer vaccine AGEN2017

{
  "id": "MLC-T-ONC-015481",
  "term": "neoantigen-HSP70 peptide cancer vaccine AGEN2017",
  "field": "Oncology and biomedicine",
  "definition": "A proprietary, personalized autologous synthetic cancer vaccine composed of patient-specific synthetic cancer neo-epitopes complexed with heat shock protein 70 (HSP 70; HSP70), with potential immunostimulating and antineoplastic activities. Upon administration of the neoantigen-HSP70 peptide cancer vaccine AGEN2017, the HSPs present the neoantigens to antigen presenting cells (APCs) and help elicit a potent neoantigen-specific T-cell-based anti-tumor immune response, thereby killing the neoantigen-expressing cancer cells. HSP70 is able to the transport the neo-epitopes, activate APCs and enhance the T-cell-mediated immune response.",
  "synonyms": [
    "AutoSynVax vaccine",
    "ASV AGEN2017",
    "AutoSynVax AGEN2017",
    "neoantigen vaccine AGEN2017",
    "autologous cancer vaccine AGEN2017"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/neoantigen-hsp70-peptide-cancer-vaccine-agen2017/"
}