Human papillomavirus 16 E7 peptide

{
  "id": "MLC-T-ONC-014248",
  "term": "Human papillomavirus 16 E7 peptide",
  "field": "Oncology and biomedicine",
  "definition": "A synthetic peptide sequence of human papillomavirus (HPV) E7 nuclear protein which is used to produce vaccines against HPV infection and HPV-related neoplasms. HPV E7 oncogenic protein binds the retinoblastoma tumor suppressor protein, pRB, as well as a number of other cellular proteins, and serves as a transcriptional activator. This protein is important in the induction and maintenance of cellular transformation and is co-expressed in the majority of HPV-containing carcinomas.",
  "synonyms": [
    "HPV-16 E7",
    "HPV16 E7"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/human-papillomavirus-16-e7-peptide/"
}