PI3Ka/mTOR inhibitor PKI-179

{
  "id": "MLC-T-ONC-016040",
  "term": "PI3Ka/mTOR inhibitor PKI-179",
  "field": "Oncology and biomedicine",
  "definition": "A second generation, small-molecule mimetic of ATP that targets the mammalian target of rapamycin (mTOR) with potential antineoplastic activity. PKI-179 selectively inhibits mTOR and phosphoinositide-3-kinase (PI3K) alpha. By inhibiting the PI3K/mTOR signaling pathway, this agent may inhibit tumor cell proliferation and survival.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/pi3ka-mtor-inhibitor-pki-179/"
}