PI3K inhibitor ACP-319

{
  "id": "MLC-T-ONC-016026",
  "term": "PI3K inhibitor ACP-319",
  "field": "Oncology and biomedicine",
  "definition": "An orally available inhibitor of phosphatidylinositol 3-kinase (PI3K), with potential antineoplastic activity. PI3K inhibitor ACP-319 inhibits PI3K, which prevents the activation of the PI3K/AKT (protein kinase B)-mediated signaling pathway. This results in the inhibition of growth and survival of PI3K-overexpressing tumor cells. Activation of the PI3K signaling pathway is frequently associated with tumorigenesis.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/pi3k-inhibitor-acp-319/"
}