MLchartDataset catalogue

Pixantrone dimaleate

Term · Oncology and biomedicine · MLC-T-ONC-016096

The dimaleate salt of a synthetic, noncardiotoxic aza-anthracenedione analogue with potential antineoplastic activity. Pixantrone intercalates into DNA and induces topoisomerase II-mediated DNA strand crosslinks, resulting in inhibition of DNA replication and tumor cell cytotoxicity.

Table 1. Record
IdentifierMLC-T-ONC-016096
FieldOncology and biomedicine
Synonymspixantrone maleate
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON 
{
  "id": "MLC-T-ONC-016096",
  "term": "Pixantrone dimaleate",
  "field": "Oncology and biomedicine",
  "definition": "The dimaleate salt of a synthetic, noncardiotoxic aza-anthracenedione analogue with potential antineoplastic activity. Pixantrone intercalates into DNA and induces topoisomerase II-mediated DNA strand crosslinks, resulting in inhibition of DNA replication and tumor cell cytotoxicity.",
  "synonyms": [
    "pixantrone maleate"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/pixantrone-dimaleate/"
}

Record 13,285 of 17,717 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.