MLchartDataset catalogue

picoplatin

Term · Oncology and biomedicine · MLC-T-ONC-016065

A new generation organic platinum analog with an extended spectrum of antineoplastic activity. Designed to overcome platinum drug resistance, picoplatin alkylates DNA, forming both inter- and intra-strand cross-linkages, resulting in inhibition of DNA replication and transcription, and the induction of apoptosis.

Table 1. Record
IdentifierMLC-T-ONC-016065
FieldOncology and biomedicine
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON
{
  "id": "MLC-T-ONC-016065",
  "term": "picoplatin",
  "field": "Oncology and biomedicine",
  "definition": "A new generation organic platinum analog with an extended spectrum of antineoplastic activity. Designed to overcome platinum drug resistance, picoplatin alkylates DNA, forming both inter- and intra-strand cross-linkages, resulting in inhibition of DNA replication and transcription, and the induction of apoptosis.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/picoplatin/"
}

Record 13,232 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.