MLchartDataset catalogue

Ormaplatin

Term · Oncology and biomedicine · MLC-T-ONC-015710

A platinum(IV) analogue with antineoplastic activity. Ormaplatin alkylates DNA, forming both inter- and intra-strand platinum-DNA crosslinks, which result in inhibition of DNA replication and transcription and cell-cycle nonspecific cytotoxicity.

Table 1. Record
IdentifierMLC-T-ONC-015710
FieldOncology and biomedicine
Synonymstetraplatin
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON 
{
  "id": "MLC-T-ONC-015710",
  "term": "Ormaplatin",
  "field": "Oncology and biomedicine",
  "definition": "A platinum(IV) analogue with antineoplastic activity. Ormaplatin alkylates DNA, forming both inter- and intra-strand platinum-DNA crosslinks, which result in inhibition of DNA replication and transcription and cell-cycle nonspecific cytotoxicity.",
  "synonyms": [
    "tetraplatin"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/ormaplatin/"
}

Record 12,348 of 17,717 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.