MLchartDataset catalogue

pan-HER kinase inhibitor AC480

Term · Oncology and biomedicine · MLC-T-ONC-015793

An orally bioavailable pan-HER tyrosine kinase inhibitor with potential antineoplastic activity. BMS-599626 inhibits human epidermal growth factor receptors (HER) HER1, HER2 and HER4, thereby inhibiting the proliferation of tumor cells that overexpress these receptors.

Table 1. Record
IdentifierMLC-T-ONC-015793
FieldOncology and biomedicine
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON 
{
  "id": "MLC-T-ONC-015793",
  "term": "pan-HER kinase inhibitor AC480",
  "field": "Oncology and biomedicine",
  "definition": "An orally bioavailable pan-HER tyrosine kinase inhibitor with potential antineoplastic activity. BMS-599626 inhibits human epidermal growth factor receptors (HER) HER1, HER2 and HER4, thereby inhibiting the proliferation of tumor cells that overexpress these receptors.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/pan-her-kinase-inhibitor-ac480/"
}

Record 12,582 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.