MLchartDataset catalogue

PD-1

Term · Oncology and biomedicine · MLC-T-ONC-006414

A protein found on T cells (a type of immune cell) that helps keep the body’s immune responses in check. When PD-1 is bound to another protein called PD-L1, it helps keep T cells from killing other cells, including cancer cells. Some anticancer drugs, called immune checkpoint inhibitors, are used to block PD-1. When this protein is blocked, the “brakes” on the immune system are released and the ability of T cells to kill cancer cells is increased.

Table 1. Record
IdentifierMLC-T-ONC-006414
FieldOncology and biomedicine
ReferencesNCI Dictionary of Cancer Terms
See alsoimmune checkpoint inhibitor
Record as JSON
{
  "id": "MLC-T-ONC-006414",
  "term": "PD-1",
  "field": "Oncology and biomedicine",
  "definition": "A protein found on T cells (a type of immune cell) that helps keep the body’s immune responses in check. When PD-1 is bound to another protein called PD-L1, it helps keep T cells from killing other cells, including cancer cells. Some anticancer drugs, called immune checkpoint inhibitors, are used to block PD-1. When this protein is blocked, the “brakes” on the immune system are released and the ability of T cells to kill cancer cells is increased.",
  "see_also": [
    "immune checkpoint inhibitor"
  ],
  "references": [
    "NCI Dictionary of Cancer Terms"
  ],
  "url": "https://mlchart.com/terminology/oncology/pd-1/"
}

Record 12,780 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.