PD-1
Term · Oncology and biomedicine · MLC-T-ONC-006414
A protein found on T cells (a type of immune cell) that helps keep the body’s immune responses in check. When PD-1 is bound to another protein called PD-L1, it helps keep T cells from killing other cells, including cancer cells. Some anticancer drugs, called immune checkpoint inhibitors, are used to block PD-1. When this protein is blocked, the “brakes” on the immune system are released and the ability of T cells to kill cancer cells is increased.
| Identifier | MLC-T-ONC-006414 |
|---|---|
| Field | Oncology and biomedicine |
| References | NCI Dictionary of Cancer Terms |
| See also | immune checkpoint inhibitor |
Record as JSON
{
"id": "MLC-T-ONC-006414",
"term": "PD-1",
"field": "Oncology and biomedicine",
"definition": "A protein found on T cells (a type of immune cell) that helps keep the body’s immune responses in check. When PD-1 is bound to another protein called PD-L1, it helps keep T cells from killing other cells, including cancer cells. Some anticancer drugs, called immune checkpoint inhibitors, are used to block PD-1. When this protein is blocked, the “brakes” on the immune system are released and the ability of T cells to kill cancer cells is increased.",
"see_also": [
"immune checkpoint inhibitor"
],
"references": [
"NCI Dictionary of Cancer Terms"
],
"url": "https://mlchart.com/terminology/oncology/pd-1/"
}
Record 12,780 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.