Penicillamine

{
  "id": "MLC-T-ONC-006476",
  "term": "Penicillamine",
  "field": "Oncology and biomedicine",
  "definitions": [
    "A drug that removes copper from the body and is used to treat diseases in which there is an excess of copper. It is also being studied as a possible angiogenesis inhibitor in the treatment of brain tumors.",
    "A beta dimethyl analog of the amino acid cysteine. As a degradation product of penicillin antibiotics, penicillamine chelates with heavy metals and increases their urinary excretion. Possessing antineoplastic properties, penicillamine induces apoptosis by a p53-mediated mechanism and inhibits angiogenesis by chelating with copper, a cofactor for angiogenesis."
  ],
  "synonyms": [
    "D-mercaptovaline",
    "D-Penicillamine",
    "Depamine"
  ],
  "references": [
    "NCI Dictionary of Cancer Terms",
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/penicillamine/"
}