succimer
Term · Oncology and biomedicine · MLC-T-ONC-016898
An orally active mercaptodicarboxylic acid, with heavy metal chelating activity. As a strong chelator, succimer is able to bind to heavy metals, such as lead, in the bloodstream, thereby forming a water-soluble complex that can be eliminated via urinary excretion. This prevents heavy metal poisoning. In addition, succimer is able to chelate the alpha particle emitter and radionuclide polonium Po 210 ((Po-210), thereby increasing its excretion and reducing the toxic effects of Po-210.
| Identifier | MLC-T-ONC-016898 |
|---|---|
| Field | Oncology and biomedicine |
| Abbreviation | DMSA |
| Synonyms | Meso 2, 3-Dimercaptosuccinic Acid |
| References | National Cancer Institute Thesaurus (CC BY 4.0) |
Record as JSON
{
"id": "MLC-T-ONC-016898",
"term": "succimer",
"field": "Oncology and biomedicine",
"definition": "An orally active mercaptodicarboxylic acid, with heavy metal chelating activity. As a strong chelator, succimer is able to bind to heavy metals, such as lead, in the bloodstream, thereby forming a water-soluble complex that can be eliminated via urinary excretion. This prevents heavy metal poisoning. In addition, succimer is able to chelate the alpha particle emitter and radionuclide polonium Po 210 ((Po-210), thereby increasing its excretion and reducing the toxic effects of Po-210.",
"abbreviation": "DMSA",
"synonyms": [
"Meso 2, 3-Dimercaptosuccinic Acid"
],
"references": [
"National Cancer Institute Thesaurus"
],
"url": "https://mlchart.com/terminology/oncology/succimer/"
}
Record 15,759 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.