MLchartDataset catalogue

pentamidine

Term · Oncology and biomedicine · MLC-T-ONC-015946

A synthetic derivative of amidine with antiprotozoal and antifungal activities. Although the precise mode of action of pentamidine is unclear, it appears to interact directly with the pathogen genome by binding to AT-rich regions of duplex DNA and the minor groove of DNA, thereby interfering with DNA replication.

Table 1. Record
IdentifierMLC-T-ONC-015946
FieldOncology and biomedicine
SynonymsAerosolized Pentamadine
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON
{
  "id": "MLC-T-ONC-015946",
  "term": "pentamidine",
  "field": "Oncology and biomedicine",
  "definition": "A synthetic derivative of amidine with antiprotozoal and antifungal activities. Although the precise mode of action of pentamidine is unclear, it appears to interact directly with the pathogen genome by binding to AT-rich regions of duplex DNA and the minor groove of DNA, thereby interfering with DNA replication.",
  "synonyms": [
    "Aerosolized Pentamadine"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/pentamidine/"
}

Record 12,919 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.