MLchartDataset catalogue

pegdinetanib

Term · Oncology and biomedicine · MLC-T-ONC-015905

A highly specific, synthetic peptide vascular endothelial growth factor receptor-2 (VEGFR-2) antagonist with potential antiangiogenic activity. Derived from human fibronectin with a proprietary protein engineering process, pegdinetanib may block the activation of VEGFR-2 by all known activating ligands, thereby inhibiting the growth of new tumor blood vessels.

Table 1. Record
IdentifierMLC-T-ONC-015905
FieldOncology and biomedicine
SynonymsVEGFR-2 inhibitor peptide CT-322
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON
{
  "id": "MLC-T-ONC-015905",
  "term": "pegdinetanib",
  "field": "Oncology and biomedicine",
  "definition": "A highly specific, synthetic peptide vascular endothelial growth factor receptor-2 (VEGFR-2) antagonist with potential antiangiogenic activity. Derived from human fibronectin with a proprietary protein engineering process, pegdinetanib may block the activation of VEGFR-2 by all known activating ligands, thereby inhibiting the growth of new tumor blood vessels.",
  "synonyms": [
    "VEGFR-2 inhibitor peptide CT-322"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/pegdinetanib/"
}

Record 12,843 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.