Oncology and biomedicine terminology · MLC-0111

Oncology and biomedicine terms: A (3,095)

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• ALK Inhibitor ASP3026An orally available, small molecule inhibitor of the receptor tyrosine kinase anaplastic lymphoma kinase...
• ALK inhibitor NVL-655An orally bioavailable, brain-penetrant, selective small molecule inhibitor of the receptor tyrosine kinase...
• ALK inhibitor PLB 1003An orally available small molecule inhibitor of the receptor tyrosine kinase anaplastic lymphoma kinase...
• ALK peptide vaccineA peptide cancer vaccine directed against the receptor tyrosine kinase anaplastic lymphoma kinase (ALK), with...
• ALK positiveDescribes cells that have a protein called ALK on their surface. In cancer, it is also used to describe cells...
• ALK2 inhibitor INCB000928An inhibitor of activin A receptor type 1 (activin receptor-like kinase 2; ALK2; ALK-2; ACVR1; ACTR-I), with...
• alkaliA chemical that can dissolve in water, combine with acids to form salts, and make acids less acidic. Alkalis...
• alkaline dietA dietary approach that aims to reduce acidity within the body. The diet focuses on eating foods considered...
• alkaline waterWater that has a pH above 7, that can be used to alter the conditions in the gastrointestinal (GI) tract and...
• alkalinityRefers to the amount of alkali. An alkali is a chemical that can dissolve in water, combine with acids to...
• alkalinizationA process that lowers the amount of acid in a solution. In medicine, an alkali, such as sodium bicarbonate...
• alkaloidA member of a large group of substances found in plants and in some fungi. Alkaloids contain nitrogen and can...
• ALK/c-Met inhibitor TQ-B3139An orally available, small molecule inhibitor of the receptor tyrosine kinases anaplastic lymphoma kinase...
• Alkeran TabletsA drug used to treat multiple myeloma and ovarian epithelial cancer that cannot be removed by surgery. It is...
• ALK-FAK inhibitor CEP-37440An orally available dual kinase inhibitor of the receptor tyrosine kinase anaplastic lymphoma kinase (ALK)...
• ALK/FAK/Pyk2 inhibitor CT-707An orally available inhibitor of the receptor tyrosine kinase anaplastic lymphoma kinase (ALK), focal...
• alkotinibAn orally available inhibitor of multiple kinases, including the receptor tyrosine kinase anaplastic lymphoma...
• ALK/ROS1 inhibitor XZP-3621An orally bioavailable inhibitor of the receptor tyrosine kinases anaplastic lymphoma kinase (ALK) and c-ros...
• ALK/ROS1/Met inhibitor TQ-B3101An orally available, small molecule inhibitor of the receptor tyrosine kinases anaplastic lymphoma kinase...
• ALK/TRK inhibitor TSR-011An orally available inhibitor of both the receptor tyrosine kinase anaplastic lymphoma kinase (ALK) and the...
• alkylating agentA type of drug that is used in the treatment of cancer. It interferes with the cell's DNA and inhibits cancer...
• alkylglycerol/rosemary capsulesAn orally available capsule containing alkylglycerols and Rosmarinus officinalis extracts standardized to...
• ALLA type of leukemia (blood cancer) that comes on quickly and is fast growing. In ALL, there are too many...
• all-cause mortalityA term that refers to death from any cause. In statistics, all-cause mortality is usually a measure of the...
• AllegraA drug used to treat certain allergy symptoms. It blocks a chemical released during an allergic response that...
• alleleOne of two or more alternative versions of a gene. A person inherits two alleles for each gene, one from the...
• allelic heterogeneityA term that describes when different mutations (changes) in a single gene cause the same disease or...
• allergenA substance that causes an allergic response. Examples include pollen, molds, and certain foods.
• allergic responseA hypersensitive immune reaction to a substance that normally is harmless or would not cause an immune...
• allitinibAn orally bioavailable and irreversible inhibitor of the receptor tyrosine kinases (RTKs) epidermal growth...
• alloantigen-specific allogeneic type 1 regulatory T cells T-allo10A preparation of allogeneic CD4+ cells that were ex vivo stimulated with alloantigens, which involves...
• allodepleted haploidentical T cells expressing inducible Caspase 9Allodepleted haploidentical T-lymphocytes transduced with the Gal-V pseudotyped retrovirus vector encoding...
• allodepleted T cell immunotherapeutic ATIR101A cell-based immunotherapeutic product containing T-lymphocyte-enriched leukocytes that are devoid of...
• allogeneicTaken from different individuals of the same species. Also called allogenic.
• allogeneic adenovirus-specific cytotoxic T lymphocytesA population of allogeneic cytotoxic T-lymphocytes (CTLs) specifically reactive to human adenovirus (Ad) with...
• allogeneic adipose-derived mesenchymal stem cellsA preparation of culture expanded human allogeneic adipose-derived mesenchymal stem cells (MSCs), that can...
• allogeneic AdV/CMV/EBV-specific T lymphocytesA preparation of human leukocyte antigen (HLA)-matched or HLA-mismatched, allogeneic CD4+ and CD8+ T...
• allogeneic AML antigen-expressing dendritic cell vaccineA cancer vaccine consisting of allogeneic, immortalized dendritic precursor cells derived from a patient with...
• allogeneic anti-B7-H3 CAR gamma delta T cells QH104A preparation of a subset of allogeneic T lymphocytes that express only gamma chain and delta chain T-cell...
• allogeneic anti-BCMA CAR T cells ALLO-605A preparation of allogeneic, transcription activator-like effector nuclease (TALEN)-engineered, gene-edited...
• allogeneic anti-BCMA CAR T cells P-BCMA-ALLO1An off-the-shelf (OTS) preparation composed of human allogeneic T cells and containing primarily stem cell...
• allogeneic anti-BCMA CAR-transduced T cells ALLO-715A preparation of allogeneic, ‘off-the-shelf’ (OTS), universal transcription activator-like effector nuclease...
• allogeneic anti-BCMA-CAR T cells PBCAR269AA preparation of allogeneic, off-the-shelf Tlymphocytes that have been genetically modified using a...
• allogeneic anti-BCMA/CS1 bispecific CAR-T cellsA preparation of allogeneic T lymphocytes that have been genetically modified to express a chimeric antigen...
• allogeneic anti-CD123 CAR-NK cells JD123A preparation of off-the-shelf (OTS), allogeneic natural killer (NK) cells engineered to express a chimeric...
• allogeneic anti-CD19 1XX-CAR T cells FT819A preparation of off-the-shelf (OTS) T lymphocytes, generated from an induced pluripotent stem cell (iPSC)...
• allogeneic anti-CD19 CAR double-negative T cells RJMty19An off-the-shelf (OTS) cell preparation composed of healthy, donor-derived CD4 and CD8 double-negative T...
• allogeneic anti-CD19 CAR T cells ATA3219A preparation of allogeneic human Epstein-Barr virus (EBV)-sensitized T lymphocytes that have been engineered...
• allogeneic anti-CD19 CAR T cells PBCAR19BA preparation of allogeneic T lymphocytes that have been genetically modified to express a chimeric antigen...
• allogeneic anti-CD19 CAR-gamma/delta T cells QH103A preparation of a subset of allogeneic T lymphocytes that express only gamma chain and delta chain T-cell...
• allogeneic anti-CD19 CAR-NK cells QN-019aA preparation of allogeneic natural killer (NK) cells engineered to express a chimeric antigen receptor (CAR)...
• allogeneic anti-CD19 CAR-T cells ALLO-501AA preparation of allogeneic, frozen, 'off-the-shelf', universal transcription activator-like effector...
• allogeneic anti-CD19 gamma-delta CAR-T cells UTAA09A preparation of a subset of allogeneic T lymphocytes that express only gamma chain and delta chain T-cell...
• allogeneic anti-CD19 T cells ThisCART19AA preparation of allogeneic engineered T lymphocytes expressing a lentiviral vector encoding chimeric antigen...
• allogeneic anti-CD19 universal CAR-T cells CTA101A preparation of allogeneic, off-the-shelf (OTS), universal, gene-edited T lymphocytes expressing a chimeric...
• allogeneic anti-CD19-CAR-CD28-IL-15-expressing natural killer T cellsA preparation of allogeneic natural killer T lymphocytes (NKTs) that have been engineered to express a...
• allogeneic anti-CD19/CD22 CAR-BBz T cellsA preparation of allogeneic T lymphocytes that have been transduced with a bivalent lentiviral vector...
• allogeneic anti-CD20 CAR T cells LUCAR-20SA preparation of donor-derived T lymphocytes that have been genetically modified to express a chimeric...
• allogeneic anti-CD20 CAR T cells LUCAR-20SPA preparation of donor-derived T lymphocytes that have been genetically modified to express a chimeric...
• allogeneic anti-CD20-CAR T cells PBCAR20AA preparation of allogeneic, off-the-shelf (OTS), T lymphocytes, derived from healthy donors, that have been...
• allogeneic anti-CD20/CD22 universal CAR-expressing T lymphocytes UCART20x22A preparation of allogeneic, off-the-shelf (OTS), universal transcription activator-like effector nuclease...
• allogeneic anti-CD30 CAR-Epstein-Barr virus-specific T lymphocytesA preparation of allogeneic human Epstein-Barr virus (EBV)-specific T lymphocytes (EBVSTs) that have been...
• allogeneic anti-CD33 CAR NK cellsA preparation of off-the-shelf natural killer (NK) cells engineered to express a chimeric antigen receptor...
• allogeneic anti-CD33 CAR T cells VCAR33A preparation of allogeneic T lymphocytes, derived from the same matched healthy donor who provided a stem...
• allogeneic anti-CD38 DAR-T cells STI-1492A preparation of human allogeneic T lymphocytes that are gene-edited with the clustered regularly interspaced...
• allogeneic anti-CD5 CAR T cellsA preparation of allogeneic T lymphocytes that have been genetically modified to express a chimeric antigen...
• allogeneic anti-CD5-IL-15/IL-15sushi-safety switch CAR T cellsA preparation of allogeneic T lymphocytes that have been transduced with a lentiviral vector to express a...
• allogeneic anti-CD6 CAR T-regulatory cellsA preparation of allogeneic T-regulatory cells (Tregs) that have been genetically modified to express a...
• allogeneic anti-CD7 CAR T cellsA preparation of donor-derived T lymphocytes that have been genetically engineered to express a chimeric...
• allogeneic anti-CD7 CAR T cells 4SCAR7UA preparation of allogeneic, off-the-shelf (OTS), universal, gene-edited T lymphocytes expressing a...
• allogeneic anti-CD7 CAR T cells WU-CART-007A preparation of off-the-shelf (OTS) donor-derived T lymphocytes that have been genetically engineered to...
• allogeneic anti-CD7 CAR-T cells BEAM-201A preparation of off-the-shelf (OTS) donor-derived T lymphocytes that have been multiplex base-edited and...
• allogeneic anti-CD70 CAR/dnTGF-BRII-expressing gamma delta T cells ADI-270A preparation of allogeneic Vdelta1 gamma delta T lymphocytes engineered to express a chimeric antigen...
• allogeneic anti-CD70-CAR T cells ALLO-316An off-the-shelf (OTS) preparation of human allogeneic T lymphocytes obtained from healthy donors that are...
• allogeneic anti-CD70-CAR-IL-15-transduced cord blood-derived natural killer cellsA preparation of allogeneic, umbilical cord blood (CB)-derived natural killer cells (NKs) that have been...
• allogeneic anti-EGFR CAR/HLA-A*02-gated inhibitory receptor-expressing T lymphocytes A2B395A preparation of allogeneic T lymphocytes that have been genetically modified to express a chimeric antigen...
• allogeneic anti-HA-1 TCR-engineered T cells TSC-100A preparation of donor-derived T lymphocytes that have been genetically engineered to express a T-cell...
• allogeneic anti-HA-2 TCR-engineered T cells TSC-101A preparation of donor-derived T lymphocytes that have been genetically engineered to express a T-cell...
• allogeneic anti-NY-ESO-1-TCR-IL-15-transduced cord blood-derived natural killer cellsA preparation of allogeneic, umbilical cord blood (CB)-derived natural killer cells (NKs) that have been...
• allogeneic autophagosome-enriched vaccine DPV-001An off-the-shelf (OTS) autophagosome-enriched tumor vaccine composed of dendritic cell (DC)-targeting...
• allogeneic B7.1/HLA-A1 transfected tumor cell vaccineAn allogeneic whole cell vaccine, derived from irradiated allogenic tumor cells manipulated to express human...
• allogeneic BK-specific cytotoxic T lymphocytesAllogeneic cytotoxic T lymphocytes (CTLs) that are specifically reactive to BK virus (BKV), with potential...
• allogeneic bone marrow transplantA procedure in which a patient receives healthy stem cells (blood-forming cells) from a donor to replace...
• allogeneic calibrated release IL-15-expressing logic-gated gene circuit anti-CD33/FLT3 CAR-NK cells SENTI-202A preparation of off-the-shelf (OTS) natural killer (NK) cells engineered to express three chimeric proteins...
• allogeneic CAR T cells CT0594CPA preparation of allogeneic T lymphocytes that have been genetically modified to express chimeric antigen...
• allogeneic CD123CAR-CD28-CD3zeta-EGFRt-expressing T lymphocytesA preparation of genetically modified allogeneic T cells transduced with a replication-incompetent...
• allogeneic CD123-specific universal CAR123-expressing T lymphocytesAllogeneic, off-the-shelf, universal transcription activator-like effector nuclease (TALEN)-engineered T...
• allogeneic CD16-expressing natural killer cells CYNK-101A population of cryopreserved, off-the-shelf (OTS) allogeneic natural killer (NK) cells derived from human...
• allogeneic CD19-CAR CD45RA-negative T cellsA preparation of allogeneic T lymphocytes, depleted of CD45RA-positive cells, that have been genetically...
• allogeneic CD19CAR-CD28-CD3-zeta-expressing T lymphocytesA preparation of allogeneic, donor-derived T lymphocytes that have been genetically modified to express a...
• allogeneic CD19CAR-transfected cytokine-induced killer cellsA preparation of allogeneic cytokine-induced killer (CIK) cells derived from peripheral blood mononuclear...
• allogeneic CD19/CD20-specific CAR-T cells P-CD19CD20-ALLO1An off-the-shelf (OTS) preparation of human allogeneic T lymphocytes containing primarily stem cell memory T...
• allogeneic CD19-OX40-CD3zeta-CAR-mbIL-15-expressing natural killer cells NKX019A preparation of off-the-shelf (OTS), allogeneic and ex vivo expanded natural killer cells (NKs) that are...
• allogeneic CD19-specific CAR-modified CD8 plus central memory-derived virus-specific T cellsA preparation of allogeneic Epstein-Barr virus (EBV)- and human cytomegalovirus (CMV)-specific CD8+ central...
• allogeneic CD19-specific universal CAR19-expressing T lymphocytesA preparation of allogeneic, frozen, ‘off-the-shelf’, universal transcription activator-like effector...
• allogeneic CD22-specific universal CAR-expressing T lymphocytes UCART22A preparation of allogeneic, off-the-shelf (OTS), universal transcription activator-like effector nuclease...
• allogeneic CD25/Treg-depleted donor lymphocytesA preparation of allogeneic peripheral blood mononuclear cells (PBMCs) derived from an 8/8 HLA-matched donor...
• allogeneic CD3- CD19- CD57+ NKG2C+ NK cells FATE-NK100A preparation of pharmacologically-enriched, allogeneic natural killer (NK) cells derived from a related, but...
• allogeneic CD3- CD19- selected natural killer cellsHuman leukocyte antigen (HLA)-haploidentical donor-derived natural killer (NK) cells that are activated with...
• allogeneic CD33CAR-CD3zeta-4-1BB-expressing T lymphocytesA preparation of allogeneic T lymphocytes transduced with a lentiviral vector expressing a chimeric antigen...
• allogeneic CD34+-enriched and CD45RA-depleted PBSCsA preparation of donor-derived peripheral blood stem cells (PBSCs) that have been enriched with CD34-positive...
• allogeneic CD34-positive enriched peripheral blood stem cellsA preparation of allogeneic CD34+ selected peripheral blood stem cells (PBSCs) that can potentially be used...
• allogeneic CD34-positive E-rosetted T-cell depleted peripheral blood stem cellsA preparation of CD34+ selected peripheral blood stem cells (PBSCs) that are depleted of T cells via...
• allogeneic CD4+ memory Th1-like T cells/microparticle-bound anti-CD3/anti-CD28A preparation consisting of allogeneic, differentiated Th1-like T cells bound to T cell-stimulating...
• allogeneic CD56-positive CD3-negative natural killer cells CYNK-001A population of cryopreserved, off-the-shelf (OTS) allogeneic natural killer (NK) cells derived from human...
• allogeneic CD8+ leukemia-associated antigens specific T cells NEXI-001A preparation of allogeneic CD8+ T cells targeting multiple undisclosed leukemia-associated antigens, with...
• allogeneic CD8+ memory T cellsA preparation of allogeneic CD8+ memory T cells from the same donor of hematopoietic cell transplantation...
• allogeneic cellular vaccine 1650-GA pluripotent, allogeneic, tumor cell vaccine composed of irradiated tumor cells from the non-small cell lung...
• allogeneic CMV antigen-specific CD4+/CD8+ T lymphocytesA population of allogeneic T lymphocytes specifically reactive to cytomegalovirus (CMV) with potential...
• allogeneic CMV/AdV-specific cytotoxic T lymphocytesA population of allogeneic cytotoxic T lymphocytes (CTLs) specifically reactive to cytomegalovirus (CMV) and...
• allogeneic CRISPR-Cas9 engineered anti-CD19 CAR T cells CTX110A preparation of human allogeneic T lymphocytes transduced with a chimeric antigen receptor (CAR) specific...
• allogeneic CRISPR-Cas9 engineered anti-CD19 CAR T cells CTX112A preparation of human allogeneic T lymphocytes transduced with a chimeric antigen receptor (CAR) specific...
• allogeneic CRISPR-Cas9 engineered anti-CD70 CAR-T cells CTX131A preparation of human allogeneic T lymphocytes gene-edited with the clustered regularly interspaced short...
• allogeneic CRISPR-Cas9-engineered anti-CD70 CAR-T cells CTX130A preparation of human allogeneic T lymphocytes gene-edited with the clustered regularly interspaced short...
• allogeneic CRISPR-edited anti-BCMA CAR-T cells CB-011A preparation of allogeneic, off-the-shelf T lymphocytes genetically modified and clustered regularly...
• allogeneic CRISPR-edited anti-CD19 CAR T cells CB-010A preparation of allogeneic, off-the-shelf T lymphocytes genetically modified to express a chimeric antigen...
• allogeneic CRISPR-edited anti-CD19 CAR T cells PACE CART19An off-the-shelf (OTS) preparation of human allogeneic T lymphocytes transduced with a lentiviral vector...
• Allogeneic CRISPR-edited Anti-CD19 CAR T Cells PBLTT52CAR19A preparation of allogeneic T-lymphocytes transduced with a lentiviral vector encoding a chimeric antigen...
• allogeneic CRISPR-edited anti-CLL-1 CAR-T cells CB-012A preparation of allogeneic, off-the-shelf T lymphocytes genetically modified and clustered regularly...
• allogeneic CS1-specific universal CAR-expressing T lymphocytes UCARTCS1AA preparation of allogeneic, off-the-shelf (OTS), universal transcription activator-like effector nuclease...
• allogeneic cytokine-induced memory-like NK cells WU-NK-101A population of off-the-shelf (OTS) donor-derived cytokine-induced, memory-like, cytotoxic natural killer...
• allogeneic cytomegalovirus-specific cytotoxic T lymphocytesA population of allogeneic cytotoxic T lymphocytes (CTLs) specifically reactive to the herpes virus...
• allogeneic dendritic cell vaccine COMBIG-DCA cancer vaccine consisting of allogeneic, immortalized dendritic cells (DCs) loaded with tumor specific...
• allogeneic dendritic cell-myeloma idiotype vaccineA cell-based vaccine composed of allogeneic dendritic cells pulsed ex-vivo with an autologous myeloma...
• allogeneic dendritic secretomesA preparation of allogeneic dendritic cell (DC) secretomes, with potential immunostimulating and...
• allogeneic DNT cells RC1012A population of off-the-shelf (OTS) healthy, donor-derived CD4 and CD8 double-negative T lymphocytes...
• allogeneic double negative T cellsA population of healthy, donor-derived CD4 and CD8 double-negative T lymphocytes (DNTs), with potential...
• allogeneic EBV-transformed B-lymphoblastoid cell line lysate-pulsed autologous dendritic cell vaccine KSD-101A cell-based cancer vaccine composed of autologous monocyte-derived dendritic cells (DCs) pulsed with...
• allogeneic Epstein-Barr virus-specific cytotoxic T lymphocytesA preparation of allogeneic Epstein-Barr virus (EBV) specific cytotoxic T lymphocytes (CTL) with potential...
• allogeneic ex-vivo-treated peripheral blood mononuclear cellsA preparation of allogeneic peripheral blood mononuclear cells (PBMCs) treated and induced ex vivo to undergo...
• allogeneic gamma delta T cells GDKM-100A preparation of a subset of allogeneic T lymphocytes that express only gamma chain and delta chain T-cell...
• allogeneic gamma-delta T lymphocytes KB-GDT-01An off-the-shelf (OTS) preparation of unmodified, donor-derived T lymphocytes that express only gamma chain...
• allogeneic gamma-delta T lymphocytes TCB-008A preparation of ex vivo-expanded, allogeneic T lymphocytes that express only gamma chain and delta chain...
• allogeneic gene-edited CD33-knockout hematopoietic stem and progenitor cellsA preparation of human allogeneic hematopoietic stem and progenitor cells (HSPCs) that are ex-vivo...
• allogeneic gene-modified gamma delta T cellsA preparation of genetically modified allogeneic gamma delta T lymphocytes, with potential immunomodulating...
• allogeneic glial progenitor cellsAn allogeneic, off-the-shelf, preparation of purified human glial progenitor cells, with potential...
• allogeneic glioblastoma stem-like cell line lysate-pulsed autologous dendritic cell vaccineA cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with lysates from an...
• allogeneic GM-CSF-based myeloma cell vaccineAn allogeneic tumor cell vaccine containing myeloma cancer cells transfected with the granulocyte...
• allogeneic GM-CSF-secreting breast cancer vaccineAn allogenic vaccine consisting of irradiated breast cancer cells transfected with the granulocyte...
• allogeneic GM-CSF-secreting breast cancer vaccine SV-BR-1-GMA vaccine consisting of irradiated allogeneic breast cancer cells, derived from the breast cancer cell line...
• allogeneic GM-CSF-secreting lethally irradiated pancreatic tumor cell vaccineAn allogeneic tumor vaccine composed of lethally irradiated allogeneic pancreatic tumor cells that are...
• allogeneic GM-CSF-secreting lethally irradiated prostate cancer vaccineAn allogeneic whole cell vaccine expressing human granulocyte macrophage-colony stimulating factor (GM-CSF)...
• allogeneic GM-CSF-secreting lethally irradiated whole melanoma cell vaccineAn allogeneic cancer vaccine composed of lethally irradiated whole melanoma cancer cells that are genetically...
• allogeneic GM-CSF-secreting myeloma vaccineAn allogeneic plasma cell myeloma vaccine consisting two multiple myeloma cell lines, H929 and U266, admixed...
• allogeneic GM-CSF-secreting tumor vaccine PANC 10.05 pcDNA-1/GM-NeoAn allogeneic cancer vaccine composed of lethally irradiated, whole pancreatic cancer cells transfected with...
• allogeneic GM-CSF-secreting tumor vaccine PANC 6.03 pcDNA-1/GM-NeoAn allogeneic cancer vaccine composed of lethally irradiated, whole pancreatic cancer cells transfected with...
• allogeneic HAdV antigen-specific T lymphocytesA population of allogeneic T lymphocytes specifically reactive to human adenovirus (HAdV) with potential...
• allogeneic HLA A2/4-1BB ligand-expressing melanoma vaccineAn allogeneic melanoma cell vaccine derived from a cell line with high expression of melanoma associated...
• allogeneic HPV-specific CD4+ T lymphocytesA preparation of allogeneic T lymphocytes, collected from a haploidentical donor of the patient after...
• allogeneic HPV-specific cytotoxic T lymphocytesA population of allogeneic cytotoxic T lymphocytes (CTLs) that are specifically reactive to human...
• allogeneic human stem cell-derived pancreatic islet cells VX-880A preparation of allogeneic human stem cell-derived, fully differentiated functional pancreatic islet cells...
• allogeneic human T-cell progenitors SMART 101A preparation of allogeneic human T-cell progenitor cells, that can potentially be used for immune...
• allogeneic hypoimmune anti-CD19 CAR T cells SC291A preparation of human allogeneic T lymphocytes transduced with a chimeric antigen receptor (CAR) specific...
• allogeneic hypoimmune anti-CD22 CAR T cells SC262A preparation of human allogeneic CD4+ and CD8+ T lymphocytes transduced with a chimeric antigen receptor...
• allogeneic iC9/CD19-CAR-CD28-zeta-2A-IL15-transduced cord blood-derived natural killer cells TAK-007A preparation of allogeneic, umbilical cord blood (CB)-derived natural killer cells (NKs) transduced with a...
• allogeneic IL13-zetakine/HyTK-expressing-glucocorticoid resistant cytotoxic T lymphocytes GRm13Z40-2A preparation of glucocorticoid receptor (GR) negative, allogeneic cytotoxic T-lymphocytes (CTLs) expressing...
• allogeneic interleukin-17-producing CD8-positive T cellsA preparation of allogeneic human cytotoxic T lymphocytes that express the pro-inflammatory cytokine...
• allogeneic invariant natural killer T cells agenT-797A preparation of allogeneic, off-the shelf, natural killer T cells (NKTs) expressing an invariant (alpha...
• allogeneic iPSC-derived anti-CD19-CAR/IL-15-expressing NK cells CNTY-101A preparation of allogeneic natural killer (NK) cells derived from a clonal master induced pluripotent stem...
• allogeneic iPSC-derived anti-MICA/B CAR/CD16/IL-15RF-expressing CD38-eliminated NK cells FT536A preparation of allogeneic, off-the-shelf (OTS), natural killer (NK) cells derived from a clonal master...
• allogeneic irradiated melanoma cell vaccine CSF470An allogeneic cancer vaccine composed of a mixture of lethally irradiated whole melanoma cancer cells...
• allogeneic large multivalent immunogen breast cancer vaccineA cancer vaccine, containing human-specific large multivalent immunogens (LMIs) isolated from the membrane...
• allogeneic large multivalent immunogen melanoma vaccine LP2307A cancer vaccine, containing human-specific large multivalent immunogen (LMI) isolated from plasma membrane...
• allogeneic LMP1-/LMP2- specific cytotoxic T-lymphocytesA preparation of cytotoxic T-lymphocytes (CTL), specifically reactive to the Epstein-Barr virus (EBV) latent...
• allogeneic melanoma vaccine AGI-101HA cancer vaccine derived from two gentically modified human melanoma cell lines with potential antineoplastic...
• allogeneic mesothelioma tumor lysate-pulsed autologous dendritic cell vaccineA cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with a mixture of lysates...
• allogeneic most closely HLA-matched adenovirus-specific cytotoxic T lymphocytesA population of off the shelf, closely human leukocyte antigen (HLA)-matched allogeneic, ex vivo-expanded...
• allogeneic MUC1-C-specific CAR-T cells P-MUC1C-ALLO1An off-the-shelf (OTS) preparation of human allogeneic T lymphocytes containing primarily stem cell memory T...
• allogeneic multipotent adult progenitor cellsA biologic product that consists of undifferentiated stem cells, obtained from adult bone marrow or other...
• allogeneic multivirus-specific cytotoxic T lymphocytesA population of closely human leukocyte antigen (HLA)-matched, donor-derived cytotoxic T lymphocytes (CTLs)...
• allogeneic natural killer cell line MG4101A population of allogeneic, cytotoxic natural killer (NK) cells with potential antitumor activity. Allogeneic...
• allogeneic natural killer cell line NK-92A proprietary, human cytotoxic cell line composed of allogeneic, activated, interleukin-2 (IL-2)...
• allogeneic natural killer cells CHM 0201A preparation of off-the-shelf (OTS) allogeneic, natural killer (NK) cells that are activated and expanded ex...
• allogeneic natural killer cells DVX201A preparation of allogeneic natural killer (NK) cells, with potential cytolytic and antineoplastic...
• allogeneic natural killer cells IDP-023A preparation of off-the-shelf (OTS) allogeneic, natural killer (NK) cells that contains g minus NK cells...
• allogeneic natural killer cells PB103A preparation of allogeneic, natural killer (NK) cells, with potential cytolytic and antineoplastic...
• allogeneic natural killer cells SAR445419A preparation of allogeneic, off-the-shelf (OTS) ex vivo-expanded natural killer (NK) cells, with potential...
• allogeneic nicotinamide-expanded natural killer cellsAllogeneic, nicotinamide (NAM)-expanded natural killer (NK) cells, with potential cytolytic and...
• allogeneic nicotinamide-expanded natural killer cells GDA-201A preparation of allogeneic, nicotinamide (NAM)-expanded natural killer (NK) cells, with potential cytolytic...
• allogeneic NKG2D CAR memory T cellsA preparation of donor-derived memory T lymphocytes that have been genetically modified to express a chimeric...
• allogeneic NKG2DL-targeting CAR-grafted gamma delta T cellsA preparation of a subset of allogeneic T lymphocytes that express only gamma chain and delta chain T-cell...
• allogeneic NKG2D-OX40-CD3zeta-CAR-mbIL-15-expressing natural killer cells NKX101A preparation of off-the-shelf (OTS), allogeneic and ex vivo expanded natural killer cells (NKs) that are...
• allogeneic NK-like cells GAIA-102A preparation of allogeneic, off-the-shelf (OTS), ex-vivo activated and expanded natural killer (NK)-like...
• allogeneic PD-L1 tumor-targeted high-affinity natural killer cellsA preparation of natural killer (NK) cells that are derived from NK-92 cells, a human cytotoxic cell line...
• allogeneic plasmacytoid dendritic cells expressing lung tumor antigens PDC*lung01An off-the-shelf (OTS) preparation composed of irradiated allogeneic plasmacytoid dendritic cells (pDCs)...
• allogeneic polymer-encapsulated IL-2-secreting retinal pigmented epithelial cells AVB-001A preparation of polymer-encapsulated cells, obtained from the human immortalized retinal pigment epithelia...
• allogeneic regulatory T cells TRX103A preparation of off-the-shelf (OTS), allogeneic CD4+ cells engineered to mimic regulatory type 1 (Tr1)...
• allogeneic renal cell carcinoma vaccine MGN1601A whole cell vaccine comprised of irradiated allogeneic renal cell carcinoma (RCC) with potential...
• allogeneic rituximab conjugated gamma delta T cells ACE1831An off-the-shelf preparation of a subset of allogeneic T lymphocytes that express only gamma chain and delta...
• Allogeneic shRNA-based Anti-BCMA CAR T cells CYAD-211A preparation of human allogeneic, 'off-the-shelf' (OTS), non-gene edited T lymphocytes that are engineered...
• allogeneic skin-derived ABCB5-positive MSCs allo-APZ2-OTSA preparation of off-the-shelf (OTS) allogeneic human dermal ex-vivo expanded mesenchymal stromal cells...
• allogeneic stem cell transplantA procedure in which a patient receives healthy blood-forming cells (stem cells) from a donor to replace...
• allogeneic T lymphocytes expressing NY-ESO-1-C259-specific TCRGenetically engineered human allogeneic T lymphocytes that are transduced with a retroviral vector encoding a...
• allogeneic TCR alpha/beta-positive T lymphocyte-depleted peripheral blood stem cellsA preparation of allogeneic T-cell receptor (TCR) alpha/beta-positive T cell-depleted peripheral blood stem...
• allogeneic TCRa/b-depleted HA-1 minor histocompatibility antigen-reactive TCR-modified RQR8-expressing T cells BSB-1001A preparation of T-cell receptor (TCR) alpha and beta (TCRa/b)-depleted donor-derived T lymphocytes that have...
• allogeneic TCR-CD3 complex/CD16/IL-15-expressing natural killer cellsA preparation of allogeneic natural killer (NK) cells that have been engineered to express a T-cell receptor...
• allogeneic TGFBR2 KO CAR27/IL-15-expressing NK cellsA preparation of allogeneic, umbilical cord blood (CB)-derived natural killer cells (NKs) that have been...
• allogeneic third-party suicide gene-transduced anti-HLA-DPB1*0401 CD4+ T cells CTL 19A preparation of allogeneic, third-party, CD4+ T lymphocytes that specifically recognizes the human leukocyte...
• allogeneic tri-functional anti-CD19 CAR-NK cellsA preparation of allogeneic natural killer (NK) cells transduced with a retroviral vector expressing the...
• allogeneic tumor cell vaccineA vaccine composed of tumor cells isolated from the tumor of one patient, killed and processed, and...
• allogeneic umbilical cord blood-derived CXCR4-enriched T-regulatory cells CK0804A preparation of allogeneic T-regulatory cells (Tregs) derived from umbilical cord blood (UCB) and enriched...
• allogeneic umbilical cord blood-derived HSPCs NLA101A preparation of universal, off-the-shelf, ex vivo expanded, allogeneic umbilical cord blood (UCB)-derived...
• Allogeneic Variable Delta 1 Gamma-delta T-lymphocytes GDX012An off-the-shelf (OTS) preparation of allogeneic variable delta 1 (Vd1) gamma-delta (gd) T-lymphocytes, with...
• allogeneic virus-specific T lymphocytesA preparation of allogeneic donor-derived T lymphocytes that are specifically reactive to adenovirus (AdV)...
• allogeneic virus-specific T lymphocytes R-MVSTA preparation of allogeneic T lymphocytes generated from partially human leukocyte antigen (HLA)-matched...
• allogenicTaken from different individuals of the same species. Also called allogeneic.
• allograftThe transplant of an organ, tissue, or cells from one individual to another individual of the same species...
• allopathic medicineA system in which medical doctors and other health care professionals (such as nurses, pharmacists, and...
• allopurinolA drug that lowers high levels of uric acid (a byproduct of metabolism) in the blood caused by some cancer...
• allopurinol sodiumThe sodium form of allopurinol, which is a structural isomer of hypoxanthine. Allopurinol inhibits xanthine...
• allosteric ErbB inhibitor BDTX-189An orally bioavailable, irreversible, selective, small-molecule inhibitor of certain oncogenic driver...
• Allovectin-7A substance that is being studied as a gene therapy agent in the treatment of cancer. It increases the...
• all-trans retinoic acidA nutrient that the body needs in small amounts to function and stay healthy. All-trans retinoic acid is made...
• almond oilThe oil extracted from the seed fruits of Prunus amygdalus. Almond oil is typically used as a skin emollient...
• almurtideA synthetic muramyl dipeptide (MDP) H8analogue with potential immunostimulating and antineoplastic activity...
• alnodesertibAn orally bioavailable inhibitor of ataxia telangiectasia and Rad3 related (ATR) kinase, with potential...
• alnuctamabA bispecific T-cell engager (BiTE) antibody directed against both the tumor-associated antigen (TAA) human...
• alobresibAn orally bioavailable inhibitor of the Bromodomain and Extra-Terminal (BET) family of proteins, with...
• aloe vera gelA preparation of leaf pulp from the parenchymal tissue of the plant Aloe vera (Liliaceae). Aloe vera gel...
• aloe vera/chamomile/thyme topical creamA topical skin cream containing aloe vera, chamomile, and thyme, with potential anti-inflammatory, soothing...
• aloe/anise/ascorbic acid/clove/peppermint/spearmint/thyme-based mouthwashA herbal-based mouthrinse containing aloe, anise, ascorbic acid, clove, peppermint, spearmint and thyme, with...
• aloe-emodinA substance found in certain plants, including aloe vera. It belongs to a family of compounds called...
• alofanibAn inhibitor of the fibroblast growth factor receptor (FGFR) type 2 (FGFR2), with potential antineoplastic...
• alogliptinA selective, orally bioavailable, pyrimidinedione-based inhibitor of dipeptidyl peptidase 4 (DPP-4), with...
• alomfilimabA human immunoglobulin G1 (IgG1) kappa monoclonal antibody that recognizes inducible T-cell co-stimulator...
• alopeciaThe lack or loss of hair from areas of the body where hair is usually found. Alopecia can be a side effect of...
• AloxiA drug used in adults and children aged 1 month and older to prevent nausea and vomiting caused by...
• alpelisibA drug used with fulvestrant to treat postmenopausal women, and men, with hormone-receptor positive...
• alpha clash anti-IL-2 antibody fusion protein LAT010An antibody fusion protein and interleukin-2 (IL-2) immunocytokine, with potential antineoplastic activity...
• alpha emitter radiation therapyTherapy that uses a radioactive substance that gives off a type of high-energy radiation called an...
• alpha fetoprotein adenoviral vector vaccineA vaccine consisting of a recombinant adenoviral vector encoding alpha fetoprotein. After vaccination...
• alpha fetoprotein plasmid DNA vaccineA vaccine consisting of plasmid DNA encoding alpha fetoprotein. After vaccination, expressed alpha...
• alpha galactosylceramideA potent alpha galactosylceramide modified from marine-sponge that stimulates the immune system to exhibit...
• alpha hydroxyl acidOne of a group of substances that are found in several types of fruit and in milk. They are used in skin care...
• alpha V beta 1 inhibitor ATN-161A small peptide antagonist of integrin alpha5beta1 with potential antineoplastic activity. ATN-161...
• alpha V beta 8 antagonist PF-06940434An antagonist of integrin alpha v beta 8, with potential antineoplastic activity. Upon administration...
• alpha-1 antitrypsin deficiencyAn inherited condition in which the body either does not make enough of a protein called alpha-1 antitrypsin...
• alpha-1,3-galactosyltransferase-expressing allogeneic lung tumor cell vaccineAn allogeneic lung cancer vaccine with potential immunostimulating and antineoplastic activities. Derived...
• alpha-1,3-galactosyltransferase-expressing allogeneic renal cell carcinoma vaccineAn allogeneic renal cell cancer (RCC) vaccine composed of cell line-derived RCCs that are genetically...
• alpha-1-proteinase inhibitor humanHuman serum-derived alpha-1 proteinase inhibitor (alpha-1-antitrypsin or AAT) with immunomodulating and...
• alpha-adrenergic antagonistA substance that relaxes muscle tissue in blood vessels and in the prostate gland, which improves the flow of...
• alpha/beta T-cell/CD19+ B-cell-depleted unrelated or partially matched donor-derived allogeneic peripheral blood stem cellsA preparation of allogeneic peripheral blood stem cells (PBSCs) from an unrelated or partially matched...
• alpha-blockerA substance that relaxes muscle tissue in blood vessels and in the prostate gland, which improves the flow of...
• alpha-fetoproteinA protein normally produced by a fetus. Alpha-fetoprotein levels are usually undetectable in the blood of...
• alpha-fetoprotein peptide-pulsed autologous dendritic cell vaccineA cell-based cancer vaccine comprised of autologous dendritic cells pulsed with four alpha-fetoprotein (AFP)...
• alpha-folate receptor-targeting thymidylate synthase inhibitor ONX-0801An alpha-folate receptor (aFR)-mediated inhibitor of thymidylate synthase (TS), with potential antineoplastic...
• alpha-Gal AGI-134A synthetic alpha Gal (aGal) molecule, with potential immunomodulating and antineoplastic activities. Upon...
• alpha-Gal glycosphingolipidsA preparation of glycosphingolipids (GSL), containing the disaccharide epitope galactose-alpha-1,3-galactose...
• alpha-galactosylceramide-pulsed autologous dendritic cellsA cancer vaccine comprised of autologous dendritic cells (DCs) pulsed with the marine sponge glycolipid...
• alpha-lactalbumin breast cancer vaccineA breast cancer vaccine consisting of recombinant human alpha-lactalbumin (aLA), with potential...
• alpha-lactalbumin-derived synthetic peptide-lipid complex alpha1HA synthetic proteolipid complex comprised of the alpha-1 domain of alpha-lactalbumin (lactose synthase B...
• alpha-lipoic acidA substance that is being studied for its ability to protect normal cells from the side effects of...
• alpha-lipoic acid/Boswellia serrata extract/methylsulfonylmethane/bromelain dietary supplementA dietary supplement composed of the fatty acid alpha-lipoic acid (ALA), a herbal extract from the tree...
• alpha-lipoic acid-palladium/vitamin/mineral supplementA proprietary water- and lipid-soluble polymer-based nutritional supplement composed of a complex mixture of...
• alpha-methyl-4-deoxy-4-[(18)F]fluoro-D-glucopyranosideA radioconjugate and sodium-dependent glucose transporter (SGLT)-specific tracer that is composed of a...
• alpha-PD1/IL2 fusion protein AWT020A bifunctional fusion protein comprised of a monoclonal antibody directed against the human negative...
• alpha-tocopherolA nutrient that the body needs in small amounts to stay healthy and work the way it should. It is fat-soluble...
• Alpha-tocopheryloxyacetic AcidAn orally bioavailable vitamin E derivative with potential antineoplastic and immunostimulating activities...
• alpha-type-1 polarized dendritic cellsA mature polarized dendritic cell with potent immunostimulating activity. Treating dendritic cells (DCs) with...
• alphaVbeta1/8 inhibitor PLN-101095An orally bioavailable, small molecule dual inhibitor of the integrins alpha V beta 1 (aVb1) and 8 (aVb8)...
• ALPK1 agonist PTT-936An orally bioavailable innate immune agonist and activator of the cytosolic alpha-protein kinase 1 (ALPK1)...
• alprazolamA drug used to treat anxiety disorders and panic attacks. It is being studied in the treatment of nausea and...
• alprostadilA drug that is used to treat impotence (inability to have an erection) and is being studied in the treatment...
• alrizomadlinAn orally available inhibitor of human homolog of double minute 2 (HDM2; mouse double minute 2 homolog...
• alsevalimabA fully human, glycoengineered monoclonal antibody targeting B7-H4 (V-set domain-containing T-cell activation...
• ALTENSA procedure in which mild electric currents are applied to certain acupuncture points (spots on the body...
• AlteplaseA form of tissue plasminogen activator that is made in the laboratory. It helps dissolve blood clots and is...
• alterationA change resulting in something that is different from the original.
• alternative medicineTreatments that are used instead of standard treatments. Standard treatments are based on the results of...
• altiratinibAn orally bioavailable inhibitor of c-Met/hepatocyte growth factor receptor (HGFR), vascular endothelial...
• altretamineAn anticancer drug that belongs to the family of drugs called alkylating agents.
• alumA chemical substance that contains aluminum sulfate and a second chemical, usually potassium sulfate. It is...
• aluminumA metallic element that is found combined with other elements in the earth’s crust. It is also found in small...
• aluminum hydroxideAn inorganic compound containing aluminum. Used in various immunologic preparations to improve...
• aluminum hydroxide/magnesium hydroxideAn oral suspension containing aluminum hydroxide and magnesium hydroxide, with antacid effects. Aluminum...
• alunacedase alfaA recombinant, soluble glycosylated form of human angiotensin converting enzyme 2 (rhACE2) with...
• AlunbrigA drug used to treat adults with non-small cell lung cancer that has spread and is ALK positive. It is also...
• ALVAC gp100 vaccineA vaccine composed of the replication-defective plaque purified recombinant canarypox virus (ALVAC) that...
• ALVAC(2) melanoma multi-antigen vaccineA therapeutic cancer vaccine, based on a replication-defective recombinant canarypox virus (ALVAC) encoding...
• ALVAC(2)-NY-ESO-1 (M)/TRICOM vaccineA cancer vaccine consisting of a replication-defective recombinant canarypox virus [ALVAC(2)] encoding the...
• ALVAC-CEA B7.1 vaccineA cancer vaccine that uses a viral vector system derived from the canarypox virus engineered to target the...
• ALVAC-CEA vaccineA cancer vaccine made with a form of the canarypox virus that does not cause disease in people. It is being...
• ALVAC-ESO-1 vaccineA cancer vaccine consisting of a replication-defective recombinant canarypox virus (ALVAC) encoding the...
• ALVAC-hB7.1A vaccine comprise of a canarypox viral vector that carries the gene for human B7.1 (CD80 antigen) with...
• ALVAC-MART-1 vaccineA cancer vaccine containing a replication-defective recombinant canarypox virus (ALVAC), encoding an epitope...
• alvelestatAn orally bioavailable, selective and reversible inhibitor of human neutrophil elastase (NE), with potential...
• alveolar rhabdomyosarcomaA soft tissue tumor that is most common in older children and teenagers. It begins in embryonic muscle cells...
• alveolar soft part sarcomaA soft tissue tumor that is most common in older children and teenagers. It begins in the soft supporting...
• alveoliTiny air sacs at the end of the bronchioles (tiny branches of air tubes in the lungs). The alveoli are where...
• alvespimycin hydrochlorideThe hydrochloride salt of alvespimycin, an analogue of the antineoplastic benzoquinone antibiotic...
• alvimopanA synthetic trans-3,4-dimethyl-4-(3-hydroxyphenyl) piperidine with peripherally selective opioid mu receptor...
• alvocidibA substance being studied in the treatment of several types of cancer. It stops cells from dividing and may...
• alvocidib hydrochlorideThe hydrochloride salt form of alvocidib, a synthetic N-methylpiperidinyl chlorophenyl flavone compound. As...
• alvocidib prodrug TP-1287An orally bioavailable, highly soluble phosphate prodrug of alvocidib, a potent inhibitor of cyclin-dependent...
• AlymsysA drug that contains the active ingredient bevacizumab and is used to treat many different types of cancer...
• Alzheimer dementiaA brain disorder that usually starts in late middle age or old age and gets worse over time. Symptoms include...
• Alzheimer diseaseA brain disorder that usually starts in late middle age or old age and gets worse over time. Symptoms include...
• Amanita phalloidesA type of poisonous mushroom that has harmful effects on the kidneys and liver. It is responsible for most...
• amantadine hydrochlorideA drug used to treat infections caused by the influenza A virus. It blocks the ability of the virus to infect...
• amatuximabA substance being studied in the treatment of mesothelioma. Amatuximab binds to a protein called mesothelin...
• AmbienA drug used to treat insomnia (inability to sleep), and anxiety. It is a type of imidazopyridine (sedative...
• amblyomin-XA recombinant form of a toxic protein derived from the salivary glands of the Amblyomma cajennense tick that...
• amcasertibAn orally available cancer cell stemness kinase inhibitor with potential antineoplastic activity. Even though...
• amcenestrantAn orally available, nonsteroidal selective estrogen receptor degrader/downregulator (SERD), with potential...
• AMDA condition in which there is a slow breakdown of cells in the center of the retina (the light-sensitive...
• AMD 3100A drug used with granulocyte colony-stimulating factor before an autologous stem cell transplant in patients...
• amdizalisibAn orally bioavailable selective inhibitor of the delta isoform of phosphatidylinositide 3-kinase...
• amelanotic melanomaA type of skin cancer in which the cells do not make the pigment melanin. Skin lesions are often irregular...
• ameloblastomaA rare tumor that begins in the cells that form the tooth enamel (the hard, outer covering that protects the...
• AmeluzA drug that contains the active ingredient aminolevulinic acid hydrochloride and is used with photodynamic...
• American GinsengThe aromatic root of the perennial herb Panax quinquefolius, native to eastern North America. American...
• ametantroneA topoisomerase II inhibitor of the anthrapyrazole family that causes covalent cross-links in DNA of tumor...
• AmeviveA drug that is used to treat certain skin conditions and is being studied in the treatment of cutaneous...
• amezalpatAn orally bioavailable, small molecule, selective and competitive antagonist of peroxisome proliferator...
• AMG 102A substance being studied in the treatment of cancer. It binds to a protein called hepatocyte growth factor...
• AMG 162A drug used to prevent or treat certain bone problems. AMG 162 is used under the brand name Xgeva to prevent...
• AMG 531A drug used to treat thrombocytopenia (a low blood platelet count) in adults and in certain children with...
• AMG 706A substance that is being studied in the treatment of some types of cancer. It belongs to the families of...
• AMHA hormone made by the ovaries in females and the testicles in males. AMH helps to form the male and female...
• amifampridineAn organic compound derived from pyridine with potassium channel inhibition activity. Amifampridine inhibits...
• amifostineA drug used to help protect the kidneys in patients receiving cisplatin for advanced ovarian cancer and to...
• amikacinAn antibiotic drug used to treat infection. It belongs to the family of drugs called aminoglycoside...
• amikacin inhalation solutionA solution for inhalation containing the aminoglycoside antibiotic amikacin, with anti-bacterial activity...
• amikacin sulfateThe sulfate salt of amikacin, a broad-spectrum semi-synthetic aminoglycoside antibiotic, derived from...
• amilomerA synthetic microsphere formulation with arterial occlusive properties. Amilomer, a product produced by...
• amino acidOne of several molecules that join together to form proteins. There are 20 common amino acids found in...
• Amino Acid InjectionA concentrated dietary supplement for injection containing the essential amino acids leucine, isoleucine...
• amino acid sequenceThe arrangement of amino acids in a protein. Proteins can be made from 20 different kinds of amino acids, and...
• amino acid/electrolyte mixture-based dietary supplementA nutritional supplement containing a proprietary mix of amino acids and electrolytes, with potential...
• aminobenzoate potassiumThe potassium salt form of aminobenzoate, with anti-inflammatory and antifibrotic activities. Aminobenzoate...
• aminobenzoic acidA nutrient in the vitamin B complex that the body needs in small amounts to function and stay healthy...
• aminocamptothecinAn anticancer drug that belongs to the family of drugs called topoisomerase inhibitors.
• aminocamptothecin colloidal dispersionA colloidal dispersion formulation of 9-Aminocamptothecin, a water-insoluble camptothecin derivative...
• aminocaproic acidA synthetic lysine derivative with antifibrinolytic activity. Aminocaproic acid competitively inhibits...
• aminoflavone prodrug AFP464A synthetic lysyl prodrug of the amino-substituted flavone derivate aminoflavone with antiproliferative and...
• aminoglutethimideAn anticancer drug that belongs to the family of drugs called nonsteroidal aromatase inhibitors...
• aminoglycoside antibioticA substance that works against many types of bacteria and includes streptomycin, gentamicin, and neomycin. An...
• aminolevulinic acidA topically administered metabolic precursor of protoporphyrin IX. After topical administration...
• aminolevulinic acid hydrochlorideA drug used under the brand names Ameluz and Levulan Kerastick with photodynamic therapy to treat actinic...
• aminolevulinic acid intravenous formulation SONALA-001An intravenous formulation of aminolevulinic acid (ALA), a metabolic precursor of the photosensitizer...
• aminophyllineA methylxanthine and derivative of theophylline. Aminophylline relaxes smooth muscles, particularly bronchial...
• aminopterinAn anticancer drug that belongs to the family of drugs called antimetabolites.
• aminothiadiazoleA synthetic derivative of nicotinamide adenine dinucleotide (NAD). Aminothiadiazole competitively inhibits...
• amiodarone hydrochlorideA drug used to treat certain types of abnormal heart rhythms that have not gotten better with other drugs...
• amitriptyline hydrochlorideA drug that is used to treat depression and may be given to treat anxiety, sleep disorders, and pain. It is...
• amivantamabA drug used alone or with other drugs to treat adults with non-small cell lung cancer that has spread and has...
• amivantamab and recombinant human hyaluronidaseA co-formulation composed of amivantamab, a human bispecific antibody targeting both epidermal growth factor...
• amivantamab-vmjwA human bispecific antibody targeting both epidermal growth factor receptor EGFR and hepatocyte growth factor...
• AMLA fast-growing cancer in which too many myeloblasts (a type of immature white blood cell) are found in the...
• AML mRNA positive lysate loaded autologous dendritic cell vaccineA cancer vaccine consisting of autologous dendritic cells loaded with separate preparations of acute...
• AML-MRCA type of acute myeloid leukemia in which at least 20% of a patient’s blood or bone marrow is myeloblasts...
• ammoniaA gas made of nitrogen and hydrogen. It has a strong odor and can irritate the skin, eyes, nose, throat, and...
• ammonia N-13A radiopharmaceutical composed of ammonia labeled with the radioisotope nitrogen N 13 that can be used...
• ammonium tetrathiomolybdateA substance being studied in the treatment of many types of cancer. Ammonium tetrathiomolybdate removes extra...
• Ammonium TrichlorotellurateA synthetic non-toxic tellurium derivative, structurally similar to cisplatin, with immunostimulatory and...
• amnion-derived cellular cytokine solutionA topical cellular cytokine solution containing a distinct combination of growth factors and cytokines...
• amniotic fluidThe clear or slightly yellow fluid that surrounds and protects an unborn baby as it grows during pregnancy...
• amolimogene bepiplasmidA plasmid DNA-based vaccine consisting of small biodegradable poly(lactide-co-glicolide) polymer...
• amonafideA substance that is being studied in the treatment of cancer. It belongs to the families of drugs called...
• amonafide dihydrochlorideThe dihydrochloride salt of amonafide, an imide derivative of naphthalic acid. Amonafide intercalates into...
• amonafide L-malateThe malate salt of amonafide, an imide derivative of naphthalic acid, with potential antineoplastic activity...
• amorphous calcium carbonateA nutritional supplement composed of a proprietary synthetic and amorphous form of calcium carbonate, that...
• amoxicillinA drug used to treat some bacterial infections. Amoxicillin is a form of penicillin that is made in the...
• amoxicillin-clavulanate potassiumA drug used to treat bacterial infections. Adding the chemical clavulanate potassium to the antibiotic...
• AMP KRAS vaccine ELI-002A peptide-based cancer vaccine composed of the adjuvant Amphiphile (Amph; AMP)-CpG-7909, which is a...
• amphotericin BA drug used in the treatment of infections caused by fungi. It is a type of antifungal.
• amphotericin B deoxycholateThe deoxycholate salt of amphotericin B, a polyene antifungal antibiotic produced by Streptomyces nodosus...
• ampicillin sodium/sulbactam sodiumA combination formulation of the sodium salts of the antibiotic ampicillin and the beta-lactamase inhibitor...
• AmplimexonA substance that is being studied in the treatment of some types of cancer, including pancreatic, lung...
• ampullaA sac-like enlargement of a canal or duct.
• ampulla of VaterAn enlargement of the ducts from the liver and pancreas at the point where they enter the small intestine.
• ampulla of Vater cancerCancer that forms in the ampulla of Vater (an enlargement of the ducts from the liver and pancreas where they...
• ampullary cancerCancer that forms in the ampulla of Vater (an enlargement of the ducts from the liver and pancreas where they...
• amputationThe removal by surgery of a limb (arm or leg) or other body part because of injury or disease, such as...
• amrecibartAn anti-factor XI (FXI) antibody, with potential anti-thrombotic activity. Upon administration, amrecibart...
• amredobresibAn orally bioavailable inhibitor of the bromodomain and extra-terminal (BET) family of proteins with...
• amrubicinA substance being studied in the treatment of lung cancer. It is a type of anthracycline analog.
• amrubicin hydrochlorideThe hydrochloride salt of a third-generation synthetic 9-amino-anthracycline with antineoplastic activity...
• amsacrineAn anticancer drug that belongs to the family of drugs called topoisomerase inhibitors.
• amsilaroteneA retinobenzoic acid with potential antineoplastic activity. Amsilarotene inhibits retinoblastoma-gene...
• amsulostatAn orally available, small-molecule, irreversible inhibitor of all lysyl oxidases (LOX) family members, with...
• AmtagviA treatment used for adults with melanoma that has spread to other parts of the body or cannot be removed by...
• amuvatinibA substance being studied in the treatment of some types of cancer. It may block certain proteins involved in...
• amygdalinA substance found in the pits of some fruits, such as apricots, and in raw nuts and plants. Amygdalin has...
• amylaseAn enzyme that helps the body digest starches.
• amyloidosisA group of diseases in which protein builds up in certain organs (localized amyloidosis) or throughout the...
• anabolic steroidA type of steroid that is used in medicine to repair body tissues and to increase appetite and the growth of...
• anagrelideA drug that is used to decrease the number of platelets in the blood in order to prevent blood clotting.
• Anagrelide Hydrochloride AnhydrousThe hydrochloride salt of a synthetic quinazoline derivative, Anagrelide Hydrochloride reduces platelet...
• anagrelide prolonged-release formulationA prolonged-release tablet formulation containing the quinazoline anagrelide, with antiplatelet activity...
• anakinraA substance that is used to treat rheumatoid arthritis, and is being studied in the treatment of cancer...
• analHaving to do with the anus. The anus is the opening of the rectum (last part of the large intestine) to the...
• anal cancerCancer that forms in tissues of the anus. The anus is the opening of the rectum (last part of the large...
• anal dysplasiaThe abnormal growth of cells in the lining of the anal canal or in the skin around the outside of the anus...
• anal Pap smearA procedure in which cells are scraped from the lining of the anus (the opening of the rectum to the outside...
• anal Pap testA procedure in which cells are scraped from the lining of the anus (the opening of the rectum to the outside...
• anal wartA raised growth in or around the anus caused by human papillomavirus (HPV). HPV can spread by skin-to-skin...
• analgesiaPain relief.
• analgesicA drug that reduces pain. Analgesics include aspirin, acetaminophen, and ibuprofen.
• analogIn chemistry, a substance that is similar, but not identical, to another.
• analysisA process in which anything complex is separated into simple or less complex parts.
• anamorelin hydrochlorideThe orally bioavailable hydrochloride salt of a synthetic, small-molecule ghrelin mimetic with...
• anaphylactic shockA severe and sometimes life-threatening immune system reaction to an antigen that a person has been...
• anaplasticA term used to describe cancer cells that divide rapidly and have little or no resemblance to normal cells.
• anaplastic large cell lymphomaAn aggressive (fast-growing) type of non-Hodgkin lymphoma that is usually of the T-cell type. The cancer...
• anaplastic lymphoma kinaseA protein that helps control cell growth. It is made by the anaplastic lymphoma kinase (ALK) gene, which may...
• anaplastic lymphoma kinase geneA gene that makes a protein that is involved in cell growth. Mutated (changed) forms of the anaplastic...
• anaplastic lymphoma kinase inhibitorA substance that blocks the activity of a protein called anaplastic lymphoma kinase (ALK), which helps...
• anaplastic lymphoma kinase positiveDescribes cells that have a protein called ALK on their surface. In cancer, it is also used to describe cells...
• anaplastic thyroid cancerA rare, aggressive type of thyroid cancer in which the malignant (cancer) cells look very different from...
• anastomosisA procedure to connect healthy sections of tubular structures in the body after the diseased portion has been...
• anastrozoleA drug used to treat certain types of breast cancer in postmenopausal women. It is also being studied in the...
• anatomicHaving to do with anatomy (the study of the structure of a plant or animal).
• anatomistA person who has special training in anatomy (the study of the structures of animals or plants).
• anatomyThe study of the structure of a plant or animal. Human anatomy includes the cells, tissues, and organs that...
• AnaxironeA synthetic triepoxide alkylating agent with potential antineoplastic activity. Anaxirone alkylates DNA via...
• anbalcabtagene autoleucelA preparation of autologous T lymphocytes that have been genetically modified to express a chimeric antigen...
• anbenitamabAn engineered Fc-based heterodimeric bispecific monoclonal antibody, derived from trastuzumab and pertuzumab...
• anbenitamab repodatecanAn antibody-drug conjugate (ADC) composed of the bispecific monoclonal antibody anbenitamab, directed against...
• ANCA measure of the number of neutrophils in the blood. Neutrophils are a type of white blood cell. They help...
• ancestimA substance that causes blood stem cells (cells from which other types of cells develop) to change into...
• ancillary testIn a clinical trial, a medical test on a patient that is not a part of the original study design.
• ancitabine hydrochlorideThe hydrochloride salt of a cytarabine congener prodrug with antineoplastic activity. Upon administration...
• andamertinibAn orally bioavailable, mono-anilino-pyrimidine, mutant-selective epidermal growth factor receptor (EGFR)...
• andecaliximabA humanized monoclonal antibody against matrix metalloproteinase 9 (MMP-9), with potential antineoplastic...
• androblastomaA rare tumor that forms in the tissues that surround and support the ovaries. Androblastomas make a male sex...
• androgenA type of hormone that promotes the development and maintenance of male sex characteristics.
• androgen ablationTreatment to suppress or block the production or action of male hormones. This is done by having the...
• androgen antagonist APC-100An orally available, vitamin E derivative and androgen receptor (AR) antagonist with potential anti-oxidant...
• androgen deprivationTreatment to suppress or block the production or action of male hormones. This is done by having the...
• androgen receptorA protein that binds male hormones called androgens. Androgen receptors are found inside the cells of male...
• androgen receptor antagonistA substance that keeps androgens (male sex hormones) from binding to proteins called androgen receptors...
• androgen receptor antagonist BAY 1161116An orally bioavailable antagonist of the androgen receptor (AR), with potential antineoplastic activity. Upon...
• androgen receptor antagonist ONC1-0013BAn orally bioavailable antagonist of the androgen receptor (AR), with potential antineoplastic activity. Upon...
• androgen receptor antagonist SHR3680An orally bioavailable androgen receptor (AR) antagonist with potential antineoplastic activity. Upon...
• androgen receptor antagonist TAS3681An orally bioavailable inhibitor of the androgen receptor (AR), with potential antineoplastic activity. Upon...
• androgen receptor antagonist TQB3720An orally bioavailable antagonist of the androgen receptor (AR), with potential antineoplastic activity. Upon...
• androgen receptor antagonist TRC253An orally bioavailable androgen receptor (AR) antagonist, with potential antineoplastic activity. Upon oral...
• androgen receptor antisense oligonucleotide AZD5312An antisense oligonucleotide targeting the androgen receptor (AR) mRNA, with potential antineoplastic...
• Androgen Receptor Antisense Oligonucleotide EZN-4176A locked nucleic acid (LNA)-based antisense oligonucleotide targeting the androgen receptor (AR) mRNA, with...
• androgen receptor blockerA substance that keeps androgens (male sex hormones) from binding to proteins called androgen receptors...
• androgen receptor degrader AC176An orally bioavailable androgen receptor (AR) chimeric degrader, with potential antineoplastic activity. Upon...
• androgen receptor degrader ARV-766An orally bioavailable androgen receptor (AR)-targeted protein degrader, composed of an AR ligand attached to...
• androgen receptor degrader HP518An orally available androgen receptor (AR)-targeted protein degrader, using the proteolysis targeting chimera...
• androgen receptor degrader RO7656594An orally bioavailable androgen receptor (AR) degrader, with potential antineoplastic activity. Upon oral...
• androgen receptor downregulator AZD3514An orally available selective androgen receptor (AR) downregulator (SARD), with potential antineoplastic...
• androgen receptor inhibitor EPI-506An orally bioavailable, small molecule inhibitor of the N-terminal domain (NTD) of the androgen receptor...
• androgen receptor inhibitor ONCT-534An orally bioavailable dual-action androgen receptor (AR) inhibitor, with potential antineoplastic activity...
• androgen receptor ligand-binding domain-encoding plasmid DNA vaccine MVI-118A cancer vaccine containing pTVG4 plasmid DNA encoding the human androgen receptor (AR) ligand-binding domain...
• androgen receptor negativeDescribes cells that do not have a protein that binds to androgens (male hormones). Cancer cells that are...
• androgen receptor positiveDescribes cells that have a protein that binds to androgens (male hormones). Cancer cells that are androgen...
• androgen receptor/glucocorticoid receptor antagonist CB-03-10An orally bioavailable steroidal cortexolone derivative and antagonist of the androgen receptor (AR) and...
• androgen suppressionTreatment to suppress or block the production or action of male hormones. This is done by having the...
• androgen synthesis inhibitorA substance that blocks an enzyme called CYP17, which the body needs to make androgens (male hormones), such...
• androgen-dependent prostate cancerProstate cancer that needs androgens (male hormones) to grow and therefore stops growing when androgens are...
• androgen-independentDescribes the ability of tumor cells to grow in the absence of androgens (hormones that promote the...
• androgen-sensitive prostate cancerProstate cancer that needs androgens (male hormones) to grow and therefore stops growing when androgens are...
• AndrographolideA labdane diterpenoid that is produced by the Andrographis paniculata plant, which has a broad range of...
• Androstane Steroid HE3235An orally bioavailable adrenal steroid analogue with potential antineoplastic activity. Androstane steroid...
• androstanoloneA hormone made from testosterone in the prostate, testes, and certain other tissues. It is needed to develop...
• anecdotal reportAn incomplete description of the medical and treatment history of one or more patients. Anecdotal reports may...
• anemiaA condition in which the number of red blood cells is below normal.
• anesthesiaA loss of feeling or awareness caused by drugs or other substances. Anesthesia keeps patients from feeling...
• anesthesiologistA doctor who has special training in giving drugs or other agents to prevent or relieve pain during surgery...
• anestheticA drug or other substance that causes a loss of feeling or awareness. Local anesthetics cause a loss of...
• anetholtrithionA substituted dithiolthione and analog of chemopreventive agent oltipraz. Anethole trithione is a bile...
• anetholtrithioneA substance that is being studied in the treatment of cancer.
• anetumab ravtansineA fully human IgG1 monoclonal antibody directed against the cell surface glycoprotein mesothelin and...
• aneuploidyA condition in which there are extra or missing chromosomes in some or all the cells in the body. Human...
• Ang2/VEGF-binding peptides-antibody fusion protein CVX-241A fusion protein containing angiopoietin-2 (Ang2) and vascular endothelial growth factor (VEGF) derived...
• angelica rootThe root of any of a group of herbs called Angelica. It has been used in some cultures to treat certain...
• Angelica sinensis root extractAn herbal extract derived from the root of the plant Angelica sinensis with possible antiinflammatory...
• AngioceptA substance being studied in the treatment of cancer. Angiocept may prevent the growth of new blood vessels...
• angiofibromaA benign (not cancer) tumor that is made up of blood vessels and fibrous (connective) tissue. Angiofibromas...
• angiofollicular lymph node hyperplasiaA rare disorder in which benign (not cancer) growths form in lymph node tissue. There are two main ways that...
• angiogenesisBlood vessel formation. Tumor angiogenesis is the growth of new blood vessels that tumors need to grow. This...
• angiogenesis inhibitorA drug or substance that keeps new blood vessels from forming. In cancer treatment, angiogenesis inhibitors...
• angiogenesis inhibitor JI-101An orally active inhibitor of vascular endothelial growth factor receptor 2 (VEGFR2), platelet-derived growth...
• angiogramAn x-ray or computer image (CT scan or MRI) of the blood vessels and blood flow in the body. A dye may be...
• angiographyA procedure to x-ray blood vessels. The blood vessels can be seen because of an injection of a dye that shows...
• angioimmunoblastic T-cell lymphomaAn aggressive (fast-growing) type of T-cell non-Hodgkin lymphoma marked by enlarged lymph nodes and...
• angiolymphoid hyperplasia with eosinophiliaA rare benign (not cancer) tumor of small blood vessels surrounded by lymphocytes and eosinophils (types of...
• angiomyolipomaA benign (noncancer) tumor of fat and muscle tissue that usually is found in the kidney. Angiomyolipomas...
• angioplastyA procedure to enlarge the opening in a blood vessel that has become narrowed or blocked by plaque (a buildup...
• angiopoietin-2-specific fusion protein PF-04856884A humanized monoclonal antibody fused to two peptides that bind to angiopoietin 2 (Ang2; ANGPT2), with...
• angiosarcomaA type of cancer that begins in the cells that line blood vessels or lymph vessels. Cancer that begins in...
• angiostatinA protein normally made by the body. It can also be made in the laboratory, and is being studied in the...
• angiotensin-converting enzyme inhibitorA drug that is used to lower blood pressure. An angiotensin-converting enzyme inhibitor is a type of...
• AngiozymeA substance being studied in the treatment of cancer. Angiozyme is a special type of RNA made in the...
• anguidineA trichothecene mycotoxin and potent teratogen. Anguidine inhibits initiation of protein synthesis, resulting...
• ANHA form of nutrition that is given as liquids, including liquid foods, through a tube inserted into a vein...
• anhidrosisA rare condition in which the sweat glands make little or no sweat. It can affect the whole body or a small...
• anhydrous enol-oxaloacetateThe anhydrous form of enol-oxaloacetate, a small molecule blood glutamate scavenger, that can be used to...
• anhydrovinblastineAn anticancer drug that belongs to the family of drugs called mitotic inhibitors.
• anidulafunginA drug that is used to treat infections caused by fungi. It belongs to the family of drugs called antifungals.
• aniline mustardAn alkylating mustard with antineoplastic activity. Aniline mustard forms covalent linkages with nucleophilic...
• animal modelAn animal with a disease either the same as or like a disease in humans. Animal models are used to study the...
• animal studyA laboratory experiment using animals to study the development and progression of diseases. Animal studies...
• animal-assisted therapyA type of therapy that uses dogs or other pets to improve the physical and mental health of patients with...
• aniridiaA disorder in which a person is born without part or all of the iris (colored tissue at the front of the...

3,095 of 17,721 terms in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.