allogeneic anti-CD19 CAR-NK cells QN-019a
Term · Oncology and biomedicine · MLC-T-ONC-009805
A preparation of allogeneic natural killer (NK) cells engineered to express a chimeric antigen receptor (CAR) specific for the tumor-associated antigen (TAA) cluster of differentiation 19 (CD19), with potential immunomodulating and antineoplastic activities. Upon administration, the allogeneic anti-CD19 CAR-NK cells QN-019a recognize, bind to and induce selective cytotoxicity in CD19-expressing tumor cells. CD19 is a B-cell specific cell surface antigen overexpressed in B-cell lineage malignancies.
| Identifier | MLC-T-ONC-009805 |
|---|---|
| Field | Oncology and biomedicine |
| Synonyms | allogeneic CD19-targeting CAR-NK cells QN-019a |
| References | National Cancer Institute Thesaurus (CC BY 4.0) |
Record as JSON
{
"id": "MLC-T-ONC-009805",
"term": "allogeneic anti-CD19 CAR-NK cells QN-019a",
"field": "Oncology and biomedicine",
"definition": "A preparation of allogeneic natural killer (NK) cells engineered to express a chimeric antigen receptor (CAR) specific for the tumor-associated antigen (TAA) cluster of differentiation 19 (CD19), with potential immunomodulating and antineoplastic activities. Upon administration, the allogeneic anti-CD19 CAR-NK cells QN-019a recognize, bind to and induce selective cytotoxicity in CD19-expressing tumor cells. CD19 is a B-cell specific cell surface antigen overexpressed in B-cell lineage malignancies.",
"synonyms": [
"allogeneic CD19-targeting CAR-NK cells QN-019a"
],
"references": [
"National Cancer Institute Thesaurus"
],
"url": "https://mlchart.com/terminology/oncology/allogeneic-anti-cd19-car-nk-cells-qn-019a/"
}
Record 690 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.