MLchartDataset catalogue

allogeneic anti-CD19 CAR-NK cells QN-019a

Term · Oncology and biomedicine · MLC-T-ONC-009805

A preparation of allogeneic natural killer (NK) cells engineered to express a chimeric antigen receptor (CAR) specific for the tumor-associated antigen (TAA) cluster of differentiation 19 (CD19), with potential immunomodulating and antineoplastic activities. Upon administration, the allogeneic anti-CD19 CAR-NK cells QN-019a recognize, bind to and induce selective cytotoxicity in CD19-expressing tumor cells. CD19 is a B-cell specific cell surface antigen overexpressed in B-cell lineage malignancies.

Table 1. Record
IdentifierMLC-T-ONC-009805
FieldOncology and biomedicine
Synonymsallogeneic CD19-targeting CAR-NK cells QN-019a
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON
{
  "id": "MLC-T-ONC-009805",
  "term": "allogeneic anti-CD19 CAR-NK cells QN-019a",
  "field": "Oncology and biomedicine",
  "definition": "A preparation of allogeneic natural killer (NK) cells engineered to express a chimeric antigen receptor (CAR) specific for the tumor-associated antigen (TAA) cluster of differentiation 19 (CD19), with potential immunomodulating and antineoplastic activities. Upon administration, the allogeneic anti-CD19 CAR-NK cells QN-019a recognize, bind to and induce selective cytotoxicity in CD19-expressing tumor cells. CD19 is a B-cell specific cell surface antigen overexpressed in B-cell lineage malignancies.",
  "synonyms": [
    "allogeneic CD19-targeting CAR-NK cells QN-019a"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/allogeneic-anti-cd19-car-nk-cells-qn-019a/"
}

Record 690 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.