autologous anti-CD19 CAR T cells GLPG5101
Term · Oncology and biomedicine · MLC-T-ONC-011355
A preparation of autologous stem-like early memory T lymphocytes that have been genetically engineered to express a chimeric antigen receptor (CAR) specific for the tumor-associated antigen (TAA) CD19, with potential immunomodulating and antineoplastic activities. Upon administration, autologous anti-CD19 CAR T cells GLPG5101 specifically recognize and kill tumor cells expressing CD19. CD19 antigen is a B-cell specific cell surface antigen expressed in all B-cell lineage malignancies.
| Identifier | MLC-T-ONC-011355 |
|---|---|
| Field | Oncology and biomedicine |
| Synonyms | autologous anti-CD19 CAR-T cells GLPG5101 |
| References | National Cancer Institute Thesaurus (CC BY 4.0) |
Record as JSON
{
"id": "MLC-T-ONC-011355",
"term": "autologous anti-CD19 CAR T cells GLPG5101",
"field": "Oncology and biomedicine",
"definition": "A preparation of autologous stem-like early memory T lymphocytes that have been genetically engineered to express a chimeric antigen receptor (CAR) specific for the tumor-associated antigen (TAA) CD19, with potential immunomodulating and antineoplastic activities. Upon administration, autologous anti-CD19 CAR T cells GLPG5101 specifically recognize and kill tumor cells expressing CD19. CD19 antigen is a B-cell specific cell surface antigen expressed in all B-cell lineage malignancies.",
"synonyms": [
"autologous anti-CD19 CAR-T cells GLPG5101"
],
"references": [
"National Cancer Institute Thesaurus"
],
"url": "https://mlchart.com/terminology/oncology/autologous-anti-cd19-car-t-cells-glpg5101/"
}
Record 2,687 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.