MLchartDataset catalogue

autologous anti-CD19 CAR T cells GLPG5101

Term · Oncology and biomedicine · MLC-T-ONC-011355

A preparation of autologous stem-like early memory T lymphocytes that have been genetically engineered to express a chimeric antigen receptor (CAR) specific for the tumor-associated antigen (TAA) CD19, with potential immunomodulating and antineoplastic activities. Upon administration, autologous anti-CD19 CAR T cells GLPG5101 specifically recognize and kill tumor cells expressing CD19. CD19 antigen is a B-cell specific cell surface antigen expressed in all B-cell lineage malignancies.

Table 1. Record
IdentifierMLC-T-ONC-011355
FieldOncology and biomedicine
Synonymsautologous anti-CD19 CAR-T cells GLPG5101
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON
{
  "id": "MLC-T-ONC-011355",
  "term": "autologous anti-CD19 CAR T cells GLPG5101",
  "field": "Oncology and biomedicine",
  "definition": "A preparation of autologous stem-like early memory T lymphocytes that have been genetically engineered to express a chimeric antigen receptor (CAR) specific for the tumor-associated antigen (TAA) CD19, with potential immunomodulating and antineoplastic activities. Upon administration, autologous anti-CD19 CAR T cells GLPG5101 specifically recognize and kill tumor cells expressing CD19. CD19 antigen is a B-cell specific cell surface antigen expressed in all B-cell lineage malignancies.",
  "synonyms": [
    "autologous anti-CD19 CAR-T cells GLPG5101"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/autologous-anti-cd19-car-t-cells-glpg5101/"
}

Record 2,687 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.