autologous anti-CD19 CAR vector-transduced T cells pCAR-19B

{
  "id": "MLC-T-ONC-011358",
  "term": "autologous anti-CD19 CAR vector-transduced T cells pCAR-19B",
  "field": "Oncology and biomedicine",
  "definition": "A preparation of autologous T lymphocytes that have been genetically modified and transduced with a vector encoding a chimeric antigen receptor (CAR) specific for the tumor-associated antigen (TAA) cluster of differentiation (CD) 19, with potential immunostimulating and antineoplastic activities. Upon administration, autologous anti-CD19 CAR vector-transduced T cells pCAR-19B specifically recognize and kill CD19-expressing tumor cells. CD19 antigen is a B-cell specific cell surface antigen expressed in all B-cell lineage malignancies.",
  "synonyms": [
    "pCAR-19B",
    "pCAR-19B cells",
    "anti-CD19 CAR T cells pCAR-19B"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/autologous-anti-cd19-car-vector-transduced-t-cells-pcar-19b/"
}