MLchartDataset catalogue

allogeneic nicotinamide-expanded natural killer cells GDA-201

Term · Oncology and biomedicine · MLC-T-ONC-009932

A preparation of allogeneic, nicotinamide (NAM)-expanded natural killer (NK) cells, with potential cytolytic and antineoplastic activities. Upon administration, the allogeneic NAM-expanded NK cells GDA-201 may lyse cancer cells. These cells also secrete pro-inflammatory cytokines, which further stimulate an anti-tumor immune response. Ex-vivo treatment with the vitamin B3 derivative NAM increases the in-vivo homing, retention and proliferation potential of the NK cells.

Table 1. Record
IdentifierMLC-T-ONC-009932
FieldOncology and biomedicine
Synonymsallogeneic NAM-expanded NK cells GDA-201; NAM-expanded allogeneic NK cells GDA-201; NAM NKs GDA-201
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON
{
  "id": "MLC-T-ONC-009932",
  "term": "allogeneic nicotinamide-expanded natural killer cells GDA-201",
  "field": "Oncology and biomedicine",
  "definition": "A preparation of allogeneic, nicotinamide (NAM)-expanded natural killer (NK) cells, with potential cytolytic and antineoplastic activities. Upon administration, the allogeneic NAM-expanded NK cells GDA-201 may lyse cancer cells. These cells also secrete pro-inflammatory cytokines, which further stimulate an anti-tumor immune response. Ex-vivo treatment with the vitamin B3 derivative NAM increases the in-vivo homing, retention and proliferation potential of the NK cells.",
  "synonyms": [
    "allogeneic NAM-expanded NK cells GDA-201",
    "NAM-expanded allogeneic NK cells GDA-201",
    "NAM NKs GDA-201"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/allogeneic-nicotinamide-expanded-natural-killer-cells-gda-201/"
}

Record 818 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.