allogeneic nicotinamide-expanded natural killer cells

{
  "id": "MLC-T-ONC-009931",
  "term": "allogeneic nicotinamide-expanded natural killer cells",
  "field": "Oncology and biomedicine",
  "definition": "Allogeneic, nicotinamide (NAM)-expanded natural killer (NK) cells, with potential cytolytic and antineoplastic activities. Upon administration, the allogeneic NAM-expanded NK cells may lyse cancer cells. These cells also secrete pro-inflammatory cytokines, which further stimulate an anti-tumor immune response. Ex-vivo treatment with the vitamin B3 derivative NAM increases the in-vivo homing, retention and proliferation potential of the NK cells.",
  "synonyms": [
    "allogeneic NAM NK cells",
    "allogeneic NAM NKs",
    "donor nicotinamide-expanded natural killer cells"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/allogeneic-nicotinamide-expanded-natural-killer-cells/"
}