MLchartDataset catalogue

Amoxicillin-clavulanate potassium

Term · Oncology and biomedicine · MLC-T-ONC-000468

  1. A drug used to treat bacterial infections. Adding the chemical clavulanate potassium to the antibiotic amoxicillin increases the amount of time the antibiotic stays active in the body. Amoxicillin-clavulanate potassium is a type of combination antibiotic. Also called Augmentin.

  2. A combination of the semisynthetic broad-spectrum antibiotic amoxicillin and the beta-lactamase enzyme inhibitor clavulanate potassium. Clavulanate potassium increases the serum half-life of amoxicillin by inhibiting beta-lactamase-mediated metabolism of amoxicillin. Amoxicillin inhibits bacterial cell wall synthesis by binding to penicillin binding proteins and inhibiting peptidoglycan synthesis, a critical component of bacterial cell walls.

Table 1. Record
IdentifierMLC-T-ONC-000468
FieldOncology and biomedicine
SynonymsAugmentin
ReferencesNCI Dictionary of Cancer Terms; National Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON
{
  "id": "MLC-T-ONC-000468",
  "term": "Amoxicillin-clavulanate potassium",
  "field": "Oncology and biomedicine",
  "definitions": [
    "A drug used to treat bacterial infections. Adding the chemical clavulanate potassium to the antibiotic amoxicillin increases the amount of time the antibiotic stays active in the body. Amoxicillin-clavulanate potassium is a type of combination antibiotic. Also called Augmentin.",
    "A combination of the semisynthetic broad-spectrum antibiotic amoxicillin and the beta-lactamase enzyme inhibitor clavulanate potassium. Clavulanate potassium increases the serum half-life of amoxicillin by inhibiting beta-lactamase-mediated metabolism of amoxicillin. Amoxicillin inhibits bacterial cell wall synthesis by binding to penicillin binding proteins and inhibiting peptidoglycan synthesis, a critical component of bacterial cell walls."
  ],
  "synonyms": [
    "Augmentin"
  ],
  "references": [
    "NCI Dictionary of Cancer Terms",
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/amoxicillin-clavulanate-potassium/"
}

Record 1,003 of 17,717 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.