MLchartDataset catalogue

Androgen receptor blocker

Term · Oncology and biomedicine · MLC-T-ONC-000518

A substance that keeps androgens (male sex hormones) from binding to proteins called androgen receptors, which are found in normal prostate cells, some prostate cancer cells, and in cells of some other tissues. Preventing this binding blocks the effects of these hormones in the body. Treatment with androgen receptor blockers may keep prostate cancer cells from growing. Examples of androgen receptor blockers used to treat prostate cancer are apalutamide, bicalutamide, darolutamide, enzalutamide, flutamide, and nilutamide. Also called androgen receptor antagonist and antiandrogen.

Table 1. Record
IdentifierMLC-T-ONC-000518
FieldOncology and biomedicine
Synonymsandrogen receptor antagonist; antiandrogen
ReferencesNCI Dictionary of Cancer Terms
Record as JSON
{
  "id": "MLC-T-ONC-000518",
  "term": "Androgen receptor blocker",
  "field": "Oncology and biomedicine",
  "definition": "A substance that keeps androgens (male sex hormones) from binding to proteins called androgen receptors, which are found in normal prostate cells, some prostate cancer cells, and in cells of some other tissues. Preventing this binding blocks the effects of these hormones in the body. Treatment with androgen receptor blockers may keep prostate cancer cells from growing. Examples of androgen receptor blockers used to treat prostate cancer are apalutamide, bicalutamide, darolutamide, enzalutamide, flutamide, and nilutamide. Also called androgen receptor antagonist and antiandrogen.",
  "synonyms": [
    "androgen receptor antagonist",
    "antiandrogen"
  ],
  "references": [
    "NCI Dictionary of Cancer Terms"
  ],
  "url": "https://mlchart.com/terminology/oncology/androgen-receptor-blocker/"
}

Record 1,080 of 17,717 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.