Androgen receptor antagonist

{
  "id": "MLC-T-ONC-000517",
  "term": "Androgen receptor antagonist",
  "field": "Oncology and biomedicine",
  "definition": "A substance that keeps androgens (male sex hormones) from binding to proteins called androgen receptors, which are found in normal prostate cells, some prostate cancer cells, and in cells of some other tissues. Preventing this binding blocks the effects of these hormones in the body. Treatment with androgen receptor antagonists may keep prostate cancer cells from growing. Examples of androgen receptor antagonists used to treat prostate cancer are apalutamide, bicalutamide, darolutamide, enzalutamide, flutamide, and nilutamide. Also called androgen receptor blocker and antiandrogen.",
  "synonyms": [
    "androgen receptor blocker",
    "antiandrogen"
  ],
  "references": [
    "NCI Dictionary of Cancer Terms"
  ],
  "url": "https://mlchart.com/terminology/oncology/androgen-receptor-antagonist/"
}