Altretamine

{
  "id": "MLC-T-ONC-000421",
  "term": "Altretamine",
  "field": "Oncology and biomedicine",
  "definitions": [
    "An anticancer drug that belongs to the family of drugs called alkylating agents.",
    "A synthetic cytotoxic s-triazine derivative similar in structure to alkylating agent triethylenemelamin with antineoplastic activity. Although the precise mechanism by which altretamine exerts its cytotoxic effect is unknown, N-demethylation of altretamine may produce reactive intermediates which covalently bind to DNA, resulting in DNA damage."
  ],
  "abbreviation": "HMM",
  "synonyms": [
    "hemel",
    "hexaloids",
    "hexamethylamine",
    "hexamethylmelamine"
  ],
  "references": [
    "NCI Dictionary of Cancer Terms",
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/altretamine/"
}