MLchartDataset catalogue

Angelica sinensis root extract

Term · Oncology and biomedicine · MLC-T-ONC-010086

An herbal extract derived from the root of the plant Angelica sinensis with possible antiinflammatory, antispasmodic, vasodilatory, estrogenic, and antitumor activities. Angelica sinensis contains volatile oils, including safrole, isosafrole, and n-butylphthalide; coumarin derivatives, including psoralens, bergapten, osthol, imperatorin, and oxypeucedanin; and ferulic acid. The coumarin derivatives in this agent may vasodilate and relax smooth muscle and may exhibit additive anticoagulant effects. Ferulic acid, a phenolic phytochemical present in plant cell walls, may neutralize free radicals such as reactive oxygen species. In addition, Angelica sinensis extract has been shown to inhibit the growth and induce apoptosis of glioblastoma mutltiforme brain tumor cells through p53-dependent and p53-independent pathways.

Table 1. Record
IdentifierMLC-T-ONC-010086
FieldOncology and biomedicine
Synonymsdong quai; Angelica root; Angelicae sinensis radix extract; Chinese Angelica; Dang qui; female Ginseng; tanggwi; toki
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON
{
  "id": "MLC-T-ONC-010086",
  "term": "Angelica sinensis root extract",
  "field": "Oncology and biomedicine",
  "definition": "An herbal extract derived from the root of the plant Angelica sinensis with possible antiinflammatory, antispasmodic, vasodilatory, estrogenic, and antitumor activities. Angelica sinensis contains volatile oils, including safrole, isosafrole, and n-butylphthalide; coumarin derivatives, including psoralens, bergapten, osthol, imperatorin, and oxypeucedanin; and ferulic acid. The coumarin derivatives in this agent may vasodilate and relax smooth muscle and may exhibit additive anticoagulant effects. Ferulic acid, a phenolic phytochemical present in plant cell walls, may neutralize free radicals such as reactive oxygen species. In addition, Angelica sinensis extract has been shown to inhibit the growth and induce apoptosis of glioblastoma mutltiforme brain tumor cells through p53-dependent and p53-independent pathways.",
  "synonyms": [
    "dong quai",
    "Angelica root",
    "Angelicae sinensis radix extract",
    "Chinese Angelica",
    "Dang qui",
    "female Ginseng",
    "tanggwi",
    "toki"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/angelica-sinensis-root-extract/"
}

Record 1,111 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.