allogeneic ex-vivo-treated peripheral blood mononuclear cells

{
  "id": "MLC-T-ONC-009883",
  "term": "allogeneic ex-vivo-treated peripheral blood mononuclear cells",
  "field": "Oncology and biomedicine",
  "definition": "A preparation of allogeneic peripheral blood mononuclear cells (PBMCs) treated and induced ex vivo to undergo early apoptosis, with potential immunomodulating and antineoplastic activities. Upon administration of allogeneic ex-vivo-treated PBMCs, the early apoptotic cells are engulfed by macrophages and immature dendritic cells (DCs). This leads to immune modulation, which may result in immune-mediated tumor cell death.",
  "synonyms": [
    "allogeneic ex-vivo-treated PBMCs"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/allogeneic-ex-vivo-treated-peripheral-blood-mononuclear-cells/"
}