androgen receptor degrader RO7656594

{
  "id": "MLC-T-ONC-010075",
  "term": "androgen receptor degrader RO7656594",
  "field": "Oncology and biomedicine",
  "definition": "An orally bioavailable androgen receptor (AR) degrader, with potential antineoplastic activity. Upon oral administration, AR degrader RO7656594 targets, binds to and degrades AR, thereby preventing AR-mediated signaling and inhibiting the proliferation of AR-overexpressing tumor cells. AR, a hormone-regulated transcription factor, plays a key role in tumor cell proliferation in castration-resistant prostate cancer (CRPC).",
  "synonyms": [
    "AR degrader RO7656594"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/androgen-receptor-degrader-ro7656594/"
}