gridegalutamide

{
  "id": "MLC-T-ONC-014039",
  "term": "gridegalutamide",
  "field": "Oncology and biomedicine",
  "definition": "An orally bioavailable androgen receptor (AR) degrader, with potential antineoplastic activity. Upon administration, gridegalutamide causes degradation of AR, prevents AR-mediated signaling and inhibits the proliferation of AR-overexpressing tumor cells. AR plays a key role in tumor cell proliferation in castration-resistant prostate cancer (CRPC).",
  "synonyms": [
    "AR degrader CC-94676",
    "Androgen Receptor Degrader CC-94676"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/gridegalutamide/"
}