MLchartDataset catalogue

Allogeneic glial progenitor cells

Term · Oncology and biomedicine · MLC-T-ONC-009889

An allogeneic, off-the-shelf, preparation of purified human glial progenitor cells, with potential neuro-regenerative activity. Upon unilateral transplantation into spinal cord demyelinated lesions, the glial progenitor cells may integrate into the spinal cord lesion sites and differentiate into astrocytes and oligodendrocytes. Astrocytes are specialized neuroglial cells that perform many neuroprotective functions. Oligodendrocytes produce myelin and may repair damage in neurodegenerative diseases involving damaged or destroyed oligodendrocytes and myelin deficiency, such as transverse myelitis.

Table 1. Record
IdentifierMLC-T-ONC-009889
FieldOncology and biomedicine
AbbreviationGRPs
SynonymsQ-cells; allogeneic glial restricted progenitor cells
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON
{
  "id": "MLC-T-ONC-009889",
  "term": "Allogeneic glial progenitor cells",
  "field": "Oncology and biomedicine",
  "definition": "An allogeneic, off-the-shelf, preparation of purified human glial progenitor cells, with potential neuro-regenerative activity. Upon unilateral transplantation into spinal cord demyelinated lesions, the glial progenitor cells may integrate into the spinal cord lesion sites and differentiate into astrocytes and oligodendrocytes. Astrocytes are specialized neuroglial cells that perform many neuroprotective functions. Oligodendrocytes produce myelin and may repair damage in neurodegenerative diseases involving damaged or destroyed oligodendrocytes and myelin deficiency, such as transverse myelitis.",
  "abbreviation": "GRPs",
  "synonyms": [
    "Q-cells",
    "allogeneic glial restricted progenitor cells"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/allogeneic-glial-progenitor-cells/"
}

Record 775 of 17,717 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.