MLchartDataset catalogue

Amonafide dihydrochloride

Term · Oncology and biomedicine · MLC-T-ONC-010042

The dihydrochloride salt of amonafide, an imide derivative of naphthalic acid. Amonafide intercalates into DNA and inhibits topoisomerase II, resulting in protein-associated strand breaks and impaired DNA and RNA synthesis.

Table 1. Record
IdentifierMLC-T-ONC-010042
FieldOncology and biomedicine
AbbreviationBIDA
Synonymsamonafide; nafidimide; benzisoquinolinedione; amonafide hydrochloride
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON 
{
  "id": "MLC-T-ONC-010042",
  "term": "Amonafide dihydrochloride",
  "field": "Oncology and biomedicine",
  "definition": "The dihydrochloride salt of amonafide, an imide derivative of naphthalic acid. Amonafide intercalates into DNA and inhibits topoisomerase II, resulting in protein-associated strand breaks and impaired DNA and RNA synthesis.",
  "abbreviation": "BIDA",
  "synonyms": [
    "amonafide",
    "nafidimide",
    "benzisoquinolinedione",
    "amonafide hydrochloride"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/amonafide-dihydrochloride/"
}

Record 999 of 17,717 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.