MLchartDataset catalogue

Aeneic multi-virus-specific T cells ALVR106

Term · Oncology and biomedicine · MLC-T-ONC-009717

A preparation of off-the-shelf (OTS), donor-derived T lymphocytes that are specifically reactive towards four community acquired respiratory viruses: respiratory syncytial virus (RSV), influenza, parainfluenza virus (PIV), and human metapneumovirus (hMPV), with potential antiviral activity. Upon infusion into allogeneic hematopoietic stem cell transplant (HSCT), solid organ transplant (SOT) recipients or other immunocompromised patients, allogeneic multi-virus-specific T cells ALVR106 provides virus-specific cellular immunity and causes specific anti-viral effects against the four viruses RSV, influenza, PIV and hMPV. This may prevent RSV, influenza, PIV and hMPV infection, and inhibits viral-associated diseases.

Table 1. Record
IdentifierMLC-T-ONC-009717
FieldOncology and biomedicine
Synonymsallogeneic multi-VSTs ALVR106; allogeneic VSTs ALVR106
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON
{
  "id": "MLC-T-ONC-009717",
  "term": "Aeneic multi-virus-specific T cells ALVR106",
  "field": "Oncology and biomedicine",
  "definition": "A preparation of off-the-shelf (OTS), donor-derived T lymphocytes that are specifically reactive towards four community acquired respiratory viruses: respiratory syncytial virus (RSV), influenza, parainfluenza virus (PIV), and human metapneumovirus (hMPV), with potential antiviral activity. Upon infusion into allogeneic hematopoietic stem cell transplant (HSCT), solid organ transplant (SOT) recipients or other immunocompromised patients, allogeneic multi-virus-specific T cells ALVR106 provides virus-specific cellular immunity and causes specific anti-viral effects against the four viruses RSV, influenza, PIV and hMPV. This may prevent RSV, influenza, PIV and hMPV infection, and inhibits viral-associated diseases.",
  "synonyms": [
    "allogeneic multi-VSTs ALVR106",
    "allogeneic VSTs ALVR106"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/aeneic-multi-virus-specific-t-cells-alvr106/"
}

Record 502 of 17,717 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.