RSV fusion inhibitor GS-5806

{
  "id": "MLC-T-ONC-016595",
  "term": "RSV fusion inhibitor GS-5806",
  "field": "Oncology and biomedicine",
  "definition": "An orally available inhibitor of human respiratory syncytial virus (RSV) fusion protein (F protein), with potential antiviral activity. Upon oral administration of GS-5806, this agent specifically binds to F protein on the viral surface, which inhibits RSV F protein-mediated fusion with the host cell membrane and prevents viral entry. This blocks RSV replication, reduces viral load, and decreases the severity of the disease. RSV F protein, a viral surface glycoprotein, plays a key role in RSV fusion with and entry into target cells.",
  "synonyms": [
    "GS-5806",
    "respiratory syncytial virus fusion inhibitor GS-5806"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/rsv-fusion-inhibitor-gs-5806/"
}