anti-RSV nanobody ALX-0171

{
  "id": "MLC-T-ONC-011078",
  "term": "anti-RSV nanobody ALX-0171",
  "field": "Oncology and biomedicine",
  "definition": "A trivalent nanobody composed of three monovalent Nb017 moieties linked with glycine-serine (GS) linkers, directed against the fusion protein (F protein) of human respiratory syncytial virus (RSV), with potential activity against RSV infections. Upon administration via nebulization and inhalation, the anti-RSV nanobody ALX-0171 targets and binds to RSV F protein, neutralizing the virus, and preventing viral entry into host cells. RSV F protein is a small envelope glycoprotein required for cytopathic syncytia formation that results from cell-to-cell fusion.",
  "synonyms": [
    "RSV-specific nanobody ALX-0171",
    "anti-RSV F nanobody ALX-0171",
    "anti-RSV protein F nanobody ALX-0171"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/anti-rsv-nanobody-alx-0171/"
}