RSV fusion protein inhibitor JNJ-53718678
Term · Oncology and biomedicine · MLC-T-ONC-016596
An orally available inhibitor of human respiratory syncytial virus (RSV) fusion protein (F protein), with potential antiviral activity. Upon oral administration of RSV fusion protein inhibitor JNJ-53718678, this agent specifically targets and binds to F protein on the viral surface, which inhibits RSV F protein-mediated fusion with the host cell membrane and prevents viral entry. This blocks RSV replication, reduces viral load, and decreases the severity of the disease. RSV F protein, a viral surface glycoprotein, plays a key role in RSV fusion with and entry into target cells.
| Identifier | MLC-T-ONC-016596 |
|---|---|
| Field | Oncology and biomedicine |
| Synonyms | respiratory syncytial virus fusion protein inhibitor JNJ-53718678; RSV F protein inhibitor JNJ-53718678 |
| References | National Cancer Institute Thesaurus (CC BY 4.0) |
Record as JSON
{
"id": "MLC-T-ONC-016596",
"term": "RSV fusion protein inhibitor JNJ-53718678",
"field": "Oncology and biomedicine",
"definition": "An orally available inhibitor of human respiratory syncytial virus (RSV) fusion protein (F protein), with potential antiviral activity. Upon oral administration of RSV fusion protein inhibitor JNJ-53718678, this agent specifically targets and binds to F protein on the viral surface, which inhibits RSV F protein-mediated fusion with the host cell membrane and prevents viral entry. This blocks RSV replication, reduces viral load, and decreases the severity of the disease. RSV F protein, a viral surface glycoprotein, plays a key role in RSV fusion with and entry into target cells.",
"synonyms": [
"respiratory syncytial virus fusion protein inhibitor JNJ-53718678",
"RSV F protein inhibitor JNJ-53718678"
],
"references": [
"National Cancer Institute Thesaurus"
],
"url": "https://mlchart.com/terminology/oncology/rsv-fusion-protein-inhibitor-jnj-53718678/"
}
Record 14,596 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.