MLchartDataset catalogue

RSV fusion protein inhibitor JNJ-53718678

Term · Oncology and biomedicine · MLC-T-ONC-016596

An orally available inhibitor of human respiratory syncytial virus (RSV) fusion protein (F protein), with potential antiviral activity. Upon oral administration of RSV fusion protein inhibitor JNJ-53718678, this agent specifically targets and binds to F protein on the viral surface, which inhibits RSV F protein-mediated fusion with the host cell membrane and prevents viral entry. This blocks RSV replication, reduces viral load, and decreases the severity of the disease. RSV F protein, a viral surface glycoprotein, plays a key role in RSV fusion with and entry into target cells.

Table 1. Record
IdentifierMLC-T-ONC-016596
FieldOncology and biomedicine
Synonymsrespiratory syncytial virus fusion protein inhibitor JNJ-53718678; RSV F protein inhibitor JNJ-53718678
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON
{
  "id": "MLC-T-ONC-016596",
  "term": "RSV fusion protein inhibitor JNJ-53718678",
  "field": "Oncology and biomedicine",
  "definition": "An orally available inhibitor of human respiratory syncytial virus (RSV) fusion protein (F protein), with potential antiviral activity. Upon oral administration of RSV fusion protein inhibitor JNJ-53718678, this agent specifically targets and binds to F protein on the viral surface, which inhibits RSV F protein-mediated fusion with the host cell membrane and prevents viral entry. This blocks RSV replication, reduces viral load, and decreases the severity of the disease. RSV F protein, a viral surface glycoprotein, plays a key role in RSV fusion with and entry into target cells.",
  "synonyms": [
    "respiratory syncytial virus fusion protein inhibitor JNJ-53718678",
    "RSV F protein inhibitor JNJ-53718678"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/rsv-fusion-protein-inhibitor-jnj-53718678/"
}

Record 14,596 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.