Adenovirus encoding human aquaporin-1

{
  "id": "MLC-T-ONC-009687",
  "term": "Adenovirus encoding human aquaporin-1",
  "field": "Oncology and biomedicine",
  "definition": "A replication-deficient, recombinant adenovirus encoding human aquaporin-1 with potential membrane water channel activity. Upon transfection of salivary glands, adenovirus encoding human aquaporin-1 (AdhAQP1) directs human aquaporin-1 (hAQP1) expression in the apical and basolateral plasma membranes of salivary secretory cells, which may result in increased saliva production. hAQP1, a water channel protein, is one of several highly conserved water channel proteins that mediate water permeability in cells of water-transporting tissues.",
  "abbreviation": "AdhAQP1",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/adenovirus-encoding-human-aquaporin-1/"
}