MLchartDataset catalogue

atovaquone

Term · Oncology and biomedicine · MLC-T-ONC-011281

A synthetic hydroxynaphthoquinone with antiprotozoal activity. Atovoquone blocks the mitochondrial electron transport at complex III of the respiratory chain of protozoa, thereby inhibiting pyrimidine synthesis, preventing DNA synthesis and leading to protozoal death.

Table 1. Record
IdentifierMLC-T-ONC-011281
FieldOncology and biomedicine
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON 
{
  "id": "MLC-T-ONC-011281",
  "term": "atovaquone",
  "field": "Oncology and biomedicine",
  "definition": "A synthetic hydroxynaphthoquinone with antiprotozoal activity. Atovoquone blocks the mitochondrial electron transport at complex III of the respiratory chain of protozoa, thereby inhibiting pyrimidine synthesis, preventing DNA synthesis and leading to protozoal death.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/atovaquone/"
}

Record 2,562 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.