autologous memory cytokine-enriched natural killer cells

{
  "id": "MLC-T-ONC-011693",
  "term": "autologous memory cytokine-enriched natural killer cells",
  "field": "Oncology and biomedicine",
  "definition": "A population of cryopreserved, autologous CD56-positive memory cytokine-enriched natural killer (NK) cells (m-ceNKs), armed with NK cell-activating surface receptors, with potential immunomodulating and antitumor activities. Autologous NK cells are pre-activated ex vivo with a cytokine cocktail, which induces the differentiation of the NK cells into immune-memory m-ceNKs, which possess a unique phenotype. The pretreated NKs exhibit enhanced cytotoxicity and increased interferon-gamma (IFN-g) production. Upon administration, the autologous m-ceNKs may recognize and kill tumor cells.",
  "synonyms": [
    "autologous m-ceNK cells",
    "autologous M-CENKs",
    "autologous memory cytokine-enriched NK cells",
    "autologous cytokine-induced memory-like NKs",
    "m-ceNK",
    "autologous memory cytokine-enhanced NK cells"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/autologous-memory-cytokine-enriched-natural-killer-cells/"
}